The tumor suppressive role and biomarker potential of PP2A in Head/Neck Cancer - Belgium
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- Currently, we are looking for an ambitious and highly motivated PhD student to work on a translational research project investigating the tumor suppressive role and biomarker potential of PP2A in Head and Neck Cancers (HNSCC).
- In particular, we will explore how the PP2A status of HNSCC tumors affects their sensitivity to radiotherapy, currently the only therapy with a certain extent of efficiency in this cancer type.
- For this purpose, we will make use of HNSCC cell models, xenograft models and a library of patient-derived tissues.
- Phenotypic studies will be complemented with studies aiming to provide molecular insights into the mechanisms of radioresistance or radiosensitization.
- Results of this PhD project are expected to be useful for more rational set-up of clinical trials, and thus for eventual translation into the clinic.
- Previous experience in cancer cell biology and use of mouse cancer models is a plus, but not a must.
- A research-minded spirit, ability to work in a team, and above all, a clear motivation for pursuing a PhD in this field, are important selection criteria.
- A Full-time PhD position (at least 4 years) in an interdisciplinary environment, with many opportunities for collaboration, both at and outside the university.
- Although funding for the project is available, the candidate is expected, and will be internally supported, to apply for independent personal funding by means of an FWO-SB fellowship application.