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Sr. Research Associate, AAV Vectorology - United States, United Kingdom, Switzerland  

CRISPR (company)


Posted on : 08 March 2017

Project Description

Position Summary
  • We are seeking a Research Associate/Sr. Research Associate to join an exciting, fast growing and well financed new company to develop novel gene editing therapies for serious diseases.
  •  The successful candidates will be integral in discovering and developing the next generation of therapies for hematological diseases. 
  • The successful candidates will have significant experience executing experiments in hematology. 
  • The candidate should be well-trained in the generation and characterization of adeno associated viral (AAV) vectors. Basic cell and molecular biology skills are desirable.
  •  The position requires enthusiasm, passion, attention to detail, and a desire to create important new medicines for patients.

  • Cell culture and virology: maintenance of tissue culture laboratory, maintenance and cryopreservation of cells, generation and purification of AAV vectors, transduction and flow cytometry 
  • Molecular biology: cloning, DNA/RNA isolation and analyses, PCR, QPCR, design and construction of optimized gene expression cassettes 
  • Assays: ELISA, Western blot, immunohistochemistry flow cytometry and data analysis 

Minimum Qualifications
  • BS or MS in biology or related discipline and 5+ years of relevant research experience 
  • Extensive experience in generation and characterization AAV vectors 
  • Extensive experience in cell culture 
  • Excellent oral and written communication skills 
  • Track record of intellectually challenging oneself to enhance scientific abilities 
  • Ability to work independently as well as part of a results oriented research team; highly organized with significant attention to detail 

Preferred Qualifications
  • Extensive experience in AAV vectorology 
  • Extensive experience with FACS, ELISA, IHC/IF 

  • Problem Solving – The ability to understand a situation, task or problem by breaking it down into smaller pieces using a systematic approach and to identify patterns and connections between situations that are not obviously related. 
  • Scientific Rigor/Attention to detail – Maintains high scientific rigor and attention to detail in designing and testing hypotheses and analyzing data. 
  • Challenges assumptions, demonstrates highly organized thinking and documentation. 
  • Creativity/Innovation – Creates a boundary-less environment that fosters curiosity and taking risks, is able to test, confirm or refute scientific hypothesis effectively and efficiently.
  •  Open to new approaches, alternative points of view and methodologies. Able to be opportunistic. 
  • Leadership – The ability to take the role as a leader of a team or work group 
  • Communication and Teamwork – Effectively expresses ideas in written, visual, and oral context. 
  • Able to work co-operatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals. 
  • Passion – Creates an exciting environment where there is a true passion for the vision of our company  Therapeutics to bring novel medicines to patients suffering from serious diseases.