This job is currently Archived,
Posted on : 29 May 2017
ProQR Therapeutics is a clinical-stage biotech company listed on NASDAQ with offices in Leiden, the Netherlands and Palo Alto, California that is focused on the development of game changing RNA based therapies for severe genetic diseases. What we offer! We offer an exciting and innovative working environment within a very committed start-up organization, great colleagues and a lot of fun! We believe in our strong culture; personal responsibility, flexible workhours and places. Off course we pay a good salary. You will have a training budget and we will pay your pension and you will get travel allowance. We have a great new office in Leiden on walking distance from Leiden Central Station. Do you think you can contribute in achieving our mission AND Do you want to work in challenging environment where your work can really make a difference? We are looking for a (Senior) Scientist Translational Dermatology As translational scientist you will work with a strong multidisciplinary team to ensure that all scientific aspects of preclinical development are integrated in the development strategy. You will have to translate preclinical science and bring it into clinical development plans. You have to communicate and collaborate with the product development teams within ProQR as well as with outside consultants, academic collaborators and CROs. You will provide input into preclinical experimental set-up and translate results and assays for clinical development activities including development of biomarker assays and possible validation of new endpoints. The translational scientist will work in the dermatology team in close cooperation with other teams in ProQR. What are you going to do: Provide scientific rationale for dosing and dosing regimen in the clinic Work creatively on development of biomarker assays and clinical outcome assessments for ultra-orphan skin diseases Provide input into preclinical efficacy and functional assays with the aim to ultimately translate suitable candidates into fit-for-purpose clinical assays Where applicable, help to devise a biospecimen sampling strategy and be in charge of obtaining suitable biospecimens for assay setup and for clinical testing Develop fit-for-purpose assays for biomarker assays and clinical outcome assessments Work on trial at home applications Liaise with external experts (KOLs and/or consultants) and collaborators to accumulate knowledge necessary Works closely with cross-functional product and expert teams Attend (scientific) meetings as representative of ProQR Contribute to regulatory documents including study reports, Investigator´s Brochures, Clinical Trial Applications and other related documents We Ask: PhD with >3 years’ experience in translational science Hands-on experience with translation of preclinical PK/PD data into a clinical development strategy (Ultra)orphan disease drug development is a must Dermatological experience is a pre Pediatric development experience is preferred Creative medicine developer who make things happen Wanting to work in a dynamic, innovative environment Excellent communication skills - verbal, presentation, and written (English is a must, Dutch is a plus) Demonstrated ability to work in a cross-functional environment Strong data review and interpretation skills Understanding GC(L)P and ICH Guidelines Ability to work under pressure Should enjoy challenging situations and have the flexibility to work in a dynamic and fast-moving environment where there is freedom to act. Do you want to be part of our devoted team of enthusiastic professionals? Do you think you can contribute in achieving our mission? Do you want to work in challenging environment where your work can really make a difference? If so, we’re looking forward to receive your application by filling out our application form: Please note that an employee screening is part of our selection process.
2333 CK Leiden The Netherlands
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