Senior Scientist, Immunohistochemist 1 - United Kingdom
- Our company is a fast-moving global bio pharmaceutical company focused on the discovery and development of innovative medicines and solutions to transform the lives of people living with severe diseases affecting the immune and central nervous systems.
- With more than 7,700 people in approximately 40 countries, the company generated revenue of € 4.2 billion in 2016. Our company invests more than 25% of revenue in cutting-edge scientific research to with the objective of solving unmet patient needs. We have a passionate, long-term commitment to the discovery and development of innovative medicines that transform the lives of people with severe diseases. At our company everything we do starts with a simple question: “How will this make a difference to the lives of people living with severe diseases?”
- We do that by connecting with patients and their families around the world living with the physical and social burdens of severe disease of the immune system and the central nervous system. Those connections offer new perspectives, drive innovation, and offer the hope of a new generation of therapies that will help to transform lives.
- This immunohistochemistry/histology opportunity is available at our site where your expertise will be critical in the support of the target biology, mechanism of action and indication selection activities of our portfolio of pre-clinical and early development programmes as well as our biomarker development projects. The breadth of work will cover a range of histological and immunohistochemical techniques ranging from tissue processing and sectioning to development of multi-antigen staining protocols, antigen activity assays as well as taking a lead role in working with CROs.
- You will join a structured career development programme designed to enhance your technical and scientific skills and equip you to further your career in industry and drug discovery. There will be early opportunities to make an impact by working in small scale teams where your contribution will be clearly visible and recognised and most importantly, will help bring solutions to transform the lives of people with severe diseases.
- Graduate/PhD with substantial experience
- Experience in tissue processing including fixation, embedding and sectioning of FFPE and frozen tissues.
- Experience in a range of histological techniques including staining procedures such as Masson’s Trichrome, Picrosirius Red,
- Development of staining protocols for novel antibodies/antigens including multi-staining approaches both fluorescent and colourimetric
- Familiarity with in situ hybridisation techniques such as RNAscope
- Awareness and compliance with the Human Tissue Act is required
- Ability to set up and lead work with CROs
- Lab supervisory and mentoring skills
- Image analysis experience would be highly advantageous
- Ability to work across groups and departments
- Successful candidates will be working in a dynamic, multi-disciplinary environment, able to apply their skills to influence projects across a spectrum of immune disease areas.
- For all roles, excellent communication skills, team working and the flexibility to work in new and challenging areas are required.
- Key attributes include a pro-active approach, strong team ethic and the ability to build relationships and work effectively across functions.
- Maintain awareness of developments in the field, be pro-active in introducing new techniques and capabilities
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