Senior Scientist, Immuno-Oncology Job - United States
Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
We are seeking a highly motivated and skilled Senior Scientist to join our Immuno-Oncology team at Merck’s Boston Site. The successful candidate will be responsible for validating novel Immuno-oncology targets and contributing to small and large molecule drug discovery programs. Responsibilities include the development and execution of experimental strategies to define biomarkers, mechanism of action and mechanism of resistance of Immuno-oncology therapeutic agents. S/he will perform in vitro experiments to determine the functional effect of candidate target activation/inhibition by using a variety of assays to interrogate immune end-points. Candidate is expected to keep abreast of published scientific literature and present his/her data at internal group meetings.
- The ideal candidate will have a BS/MS degree in the biological sciences, with a minimum of 5 years of experience in the area of oncology and/or Immuno-oncology or Immunology.
- Candidate must have expertise with multi-parameter flow cytometry, developing in vitro and in vivo assays to investigate immune function and possess a deep knowledge of technologies commonly used to assess immune endpoints.
- Candidate should have experience in primary immune cell isolation and stimulation, proliferation and apoptosis assays, immunoassay techniques/platforms (e.g. Western, ELISA, Mesoscale), as well as RT-PCR.
- Candidate should be competent in standard scientific software used for data analysis (e.g. Microsoft Excel) as well as Microsoft Word and PowerPoint and Graphpad Prism.
- Candidate should be a strong team player with excellent oral and written communication skills and with a demonstrated ability to work independently to design experiments, interpret data, troubleshoot, and suggest next steps.
- Experience in pharmaceutical drug discovery particularly using therapeutic antibodies or small molecules is desired but not essential.
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Job Title:Sr. Scientist, Biology-Discovery
Primary Location: NA-US-MA-Boston
Employee Status: Regular
Number of Openings: 1
Company Trade Name:Merck
Nearest Major Market: Boston
Job Segment: Oncology, Scientific, Scientist, Immunology, Pharmaceutical, Healthcare, Engineering, Science