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Senior Scientist DMPK Transporter - United Kingdom  

Company managed [?] Still accepting applications

Posted on : 25 June 2017

Project Description

Department Marketing Statement
  • For nearly 70 years, our company employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies.
  •  When you join our family, you will have a significant impact on the health and well-being of people across the globe. 
  • Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. 
  • In return, we’ll help you build a career that you can feel passionate about.
  • We are seeking an experienced Senior Scientist DMPK Transporter for our Discovery Sciences site.
  • The purpose of this role is to perform laboratory work, to generate, analyse, interpret, quality check and report DMPK data with a focus initially on drug transporter assays and manage client requirements. 
  •  The successful candidate will perform duties such as planning, performing and developing standard and customized protocols, interpretation of data, suggestion of next steps, quality control checks, reporting experimental data, troubleshooting, liaising with clients and project teams and understanding the H&S aspects.
  • The job role is also a learning and development opportunity and by adopting a flexible and willing attitude to learning, and attending appropriate internal or external training sessions and sharing knowledge, the individual will learn and also teach new principles and techniques to develop individual and divisional scientific capabilities and develop expert theoretical and practical scientific knowledge.
  • In addition to the general duties listed below the candidate will be expected to expand their skill set by developing their understanding of the drug discovery process and application of DMPK data to effectively progress projects with support from line management.


Requirements:
The following are minimum requirements related to the Senior Scientist DMPK Transporter position.
  • Graduate (B.Sc) in Biology, Chemistry or Life Sciences, with relevant industrial experience.
  • Relevant work experience in a DMPK laboratory undertaking drug transporter (e.g. OATP1B1, OCT1, MDR1) inhibition and substrate assays
  • Experienced in working with radiochemical and LC-MS endpoints.
  • Demonstrated theoretical and practical knowledge of drug transporter inhibition and substrate assays. 
  •  Knowledge of requirements of regulatory bodies for drug-drug interaction studies.
  • Experience of generating and reporting DMPK data and ensuring the overall quality of scientific work
  • Experienced in working with radiochemical and LC-MS endpoints.


About Us: 
  • For nearly 70 years, our employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies.  
  • When you join our family, you will have a significant impact on the health and well-being of people across the globe.  
  • Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. 
  •  In return, we’ll help you build a career that you can feel passionate about. 
  • Our company is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development.  
  • Our company also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities.  
  • Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. 
  • With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.   
  • Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015.  
  • We are passionate about our role in improving the quality of people’s lives.  
  • Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe.  
  • We have proudly supported the development of ~70% of the drugs approved by the FDA in 2016. 


Equal Employment Opportunity
Our company is an Equal Opportunity Employer M/F/Disabled/Vet