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Scientist Microbiome Sciences - United States  

Siolta Therapeutics (company)

Posted on : 12 September 2017

Project Description


Microbiome Sciences

Siolta Therapeutics is seeking highly motivated and talented technical staff scientists to provide
support for the company’s therapeutic development program focused on prevention/treatment of
airway inflammation through manipulation of the gut microbiome. The successful candidate will
work closely with other team members on preclinical studies of a rationally designed mixedspecies
therapeutic microbial consortium. The successful candidate will be technically proficient
in microbial culture, molecular techniques and experienced in animal handling.

Essential Qualifications:
  • Ph.D. in microbiology, microbial genomics, microbial ecology, microbial bioinformatics
    or other related scientific field
  • Experience with next generation sequencing and analysis
    Demonstrated aptitude in biostatistics, analysis of high-dimensional biological and
    genomic data sets, and the application of such methods to interrogate biological systems
  • Proficiency in UNIX/Linux development environment with knowledge in at least one
    analytical language (e.g. R or Matlab)
  • Must be capable of applying new knowledge and skills creatively while working both
    independently and collaboratively in fast paced development environment
  • Strong publication record
Preferred Qualifications:
  • Experience with humanized germ-free mice
  • Working knowledge of mammalian immunology
  • Participation in IND enabling studies
Key Responsibilities:
  • Generate, analyze and interpret microbiota, metagenomic and metabolomic data sets to
    identify microbial and functional ecology correlates associated with inflammation
  • Develop quantitative methods, metrics, and analytical procedures for evaluating and
    interpreting microbiome datasets as they relate to associated immunological responses of
  • Maintain current awareness of microbiome literature, emerging approaches and methods
    in microbiome genomic and systems biology analyses
  • Contribute to the development of Siolta’s intellectual property estate
Who we are:

Siolta Therapeutics is an early-stage biotech located in the San Francisco Bay Area focused on
developing microbial therapeutics to treat or prevent inflammatory disease. We are developing a
strong multi-disciplinary team of scientists to support our vision of rationally designed microbial
therapeutic development.


Siolta Therapeutics offers competitive salary, equity plans, and full benefit packages that are
commensurate with experience.