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Research / Sr. Research Scientist, Antibody Discovery Wilmington United States,  


Posted on : 13 May 2017

Project Description

  Incyte Corporation is a Wilmington, Delaware-based biopharmaceutical company focused on the discovery, development and commercialization of proprietary therapeutics, primarily for oncology. Our first commercial product, Jakafi?, is approved in the U.S. for patients with intermediate or high-risk myelofibrosis and for patients with polycythemia vera who have had an inadequate response to or are intolerant of hydroxyurea. We have a diverse and growing portfolio of product candidates, including both small and large molecules. Over the last two years Incyte has established a partnership alliance with Agenus for the discovery and development of therapeutic antibodies in the area of Immuno-oncology.  This has resulted in the initiation of two clinical development programs and a number of discovery research programs. Recently, the commitment to therapeutic antibodies was reinforced by signing a broad collaboration with Merus B.V. for the discovery and development of bispecific therapeutic antibodies in the area of oncology. Job Summary This candidate will be a part of an in vivo antibody discovery group.  He/she will be responsible for tissue culture and molecular biology assays in support of antibody discovery for therapeutic applications. Job Responsibilities                  Plan, perform, analyze, and document laboratory experiments in support of antibody discovery                  Sort and culture primary cells by FACS                  Analyze samples by ELISA and various functional assays                  Clone and sequence antibody genes                  Prioritize and manage multiple ongoing projects                  Maintain laboratory instruments Minimum Requirements                  Degree in biochemistry, molecular biology, cell biology, or related life sciences field                  BS/MS with a minimum of 5 years of laboratory experience                  Minimum 2 years of antibody discovery experience                  Knowledge and hands-on-experience with tissue culture, molecular biology, cloning, sequencing, and flow cytometry is required                  Experience with B cell cultures or hybridomas is preferred                  Experience with antibody cloning or NGS is a plus                  Demonstrated ability to document and summarize complex data                  Flexible and enthusiastic in a fast paced biotech                  Strong organization, communication, and computer skills

Locations

Wilmington DE

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