BrightOwl Loader Loading

Research Scientist, Mass Spectometry/Biophysics Slough United Kingdom,  

UCB (company)


Posted on : 21 March 2017

Project Description

Description:
  • Our company aspires to be the Patient Centric global Bio pharmaceutical leader, transforming the lives of people with severe diseases. 
  • Due to the significant growth within our New Medicines group we are now looking for an exceptional and talented Research Scientist to strengthen our capabilities. 
  • The Biophysics/Biochemistry Group is responsible for the screening of large panels of different humanized therapeutic candidates from our novel and propriety antibody discovery technology. 
  • This is achieved using a suite of biophysical/biochemical assays and techniques to select robust therapeutic candidates that are stable during manufacture and storage.  
  • We are seeking a high calibre, laboratory-based candidate, with expertise in mass spectrometry, who can quickly integrate into this highly motivated and focused team. 

  
Responsibilities:   
  • Analyse intact, folded antibody/protein molecules using different mass spectrometry methods across a number of research projects and applications. 
  • Identify and flag susceptible post-translational modifications (both in vitro and in the presence of serum) which could impact on product stability. 
  •  Validate n silico prediction packages for hydrophobic/charge patch mapping to predict aggregation stability. 
  • Set up and drive N terminal sequencing using mass spectrometry. 
  • Work flexibly and share expertise with other users of state of the art  mass spectrometry equipment (orbitrap, ion mobility, QTOF, MALDI-TOF) embedded in a wider mass spectrometry community within company  Research.   
  • Take on a scientific leadership role of mass spectrometry expertise within the Biophysics group, having a positive impact on project progression. 
  • Contribute to the development of novel technology in the Biophysics team. 
  •  Act as an ambassador for company  by proactively communicating science externally via oral communications at scientific meetings and through publications in peer reviewed scientific journals.  


Profile:   
  • A Post graduate/PhD with experience of hands-on  mass spectrometry characterisation of antibody/protein molecules using a range of different equipment, preferably within an industrial or highly regarded academic laboratory in a Biophysics/ Biochemistry environment. 
  • Proven track record of publications related to mass spectrometry applications in peer reviewed, high quality science journals. 
  • Highly motivated individual with excellent attention to detail and critical data analysis skills. 
  • Exceptional organisational skills with proven ability to deliver to tight timelines. 
  • Flexibility in learning new techniques including biophysical / biochemical analysis skills, particularly to corroborate mass spectrometry analysis. 
  • Excellent communication and team-working ability.       
    

Job Segment:  Biochemistry, Scientific, Research Scientist, Scientist, Science, Engineering, Research                       

Locations

Slough United Kingdom

Find a Job Find Candidates

Similar Jobs

More jobs from UCB

Other jobs in United Kingdom

Other jobs in Slough

Other jobs from UCB in Slough

Other similar job in Slough

Other Jobs

Most Recent Searches

Most Famous Searches

You might also like