Research Associate, Cell Biology - United States
Location = Cambridge, MA
Typical Daily Work Hours = 8am to 5pm (some flexibility in start/end times)
Weekend work & OT not required.
100% onsite work.
Extension is likely, assuming performance & business needs are good.
Located in Cambridge, MA, the Chemical Biology Group at Client Corp. is seeking a highly-skilled and motivated scientist with experience in various aspects of molecular and cell biology. The Chemical Biology Group at Client focuses on several key areas, including but not limited to: New target identification, target validation, elucidating drug mechanism of action, molecular basis of disease states, and the assessment and development of Client modalities for use in drug discovery. The successful candidate will provide key tools and assay data for use within these areas of research. This individual will have insatiable curiosity, a strong work ethic, and the ability to work equally well in a team or independently. The successful candidate will also possess the following:
Responsibilities will include, but are not limited to, the following:
• Possesses cell-based and biochemical assay development experience with a variety of readout technologies such as flow cytometry, ELISA, and immunofluorescence.
• Generates knockout, knockdown, or enzymatically inactive target protein cell systems for testing target validation hypotheses, using approaches such as siRNA, shRNA and CRISPR.
• Collaborates alongside a cross-functional team that includes chemical biologists, chemists, biochemists, and proteomics experts to develop new technologies, Client new targets, and provide solutions for project teams. Experience working in this environment is a plus.
• Excellent communication, record keeping, presentation, collaboration and organizational skills are required.
• REQUIRES BS/MS in related field; with 0-2 years (less than 2 yrs exp would require MS degree).
• Broadly trained in molecular and cell biology.
• Working understanding of siRNA, shRNA and CRISPR technologies.
• Experience independently generating precise, reliable data and skillfully analyzing the data.
• Hands-on experience in cell culture and characterization of cells from human and animal tissues is required.
• Cell-based and biochemical assay experience with a variety of readout technologies, such as, but not limited to: flow cytometry, ELISA, and immunofluorescence.
• Engage enthusiastically and effectively in disparate projects.
• Function independently within the framework of tightly knit project teams.
• Reliably execute on team responsibilities in an efficient manner.
• Be proactive, organized, and driven by a fundamental interest in contributing to science in general, and drug discovery as a whole.