Protein/Formulation Biochemist - United States
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|At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. |
|Eli Lilly & Company’s Biotechnology Discovery Research organization is responsible for discovering and optimizing novel biotherapeutic medicines (proteins, peptides, antibodies) for advancement into clinical research in key areas of unmet medical need including diabetes, oncology, immunology, neuroscience, and others. An essential component for commercial success is ensuring that drug candidates have biopharmaceutical properties that enable successful manufacturing, formulation, and drug delivery. |
The Biotechnology Discovery Research organization has recently created a new Formulation and Delivery Research Team focused on expanding capabilities in the areas of formulation, drug delivery, and early device feasibility assessment. This team will have the opportunity to work cross-functionally between Discovery and Development groups to include protein/peptide engineering, biology, ADME, toxicology, and bioproduct Development teams.
The selected individual for this position will spend roughly half of their time investigating and enhancing the developability characteristics of novel therapeutic molecules through engineering and/or formulation efforts. The other half will be devoted to gaining a better understanding of the subcutaneous compartment and factors affecting bioavailability of parenterally-administered biomolecules. Novel formulation approaches to enhance bioavailability, either through masking a molecule’s unfavorable surface property or directly altering the in vivo environment, will be undertaken to facilitate capillary/lymphatic uptake.
Some of the key responsibilities include:
|Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. . |