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Principal Scientist – Drug Metabolism & Pharmacokinetics  

Company managed [?] Still accepting applications

Posted on : 11 April 2017

Project Description

Principal Scientist – Drug Metabolism & Pharmacokinetics

Bring your experience into play in business critical drug discovery projects

If you bring solid experience within Drug Metabolism & Pharmacokinetics (DMPK), and you are looking for a job where you can be a key player in vital drug discovery projects as well as in defining the DMPK strategy going forward, you have just found it. You can look forward to being part of a successful international company that is experiencing a very exciting period of time. New projects and initiatives are taking place everywhere around you, and ambitions are higher than ever.   

Ensure drive and timely progression in exciting research projects

As Principal Scientist you will directly impact research projects with your scientific knowledge enabling timely progression based on data-driven decisions. At the same time you will get the opportunity to influence the way the department supports the research projects through scientific input to our DMPK strategy with a clear focus on implementation and execution of the strategy. In this, you will be a key driver in ensuring knowledge sharing within the department as well as across the global organisation Your primary tasks will be to:

  • Take on a DMPK lead role in drug discovery projects
  • Deliver Pharmacokinetics, PK/PD modelling and dose-to-man prediction to research projects
  • Plan and monitor internally and externally performed PK studies
  • Give input to and drive implementation of DMPK strategy in research with emphasis on PK & PK/PD
  • Coach and guide less experienced DMPK scientists

Extensive knowledge within Drug Metabolism & Pharmacokinetics

You have a Ph.D. backed by +10 years’ of industrial experience that has provided you with extensive knowledge within Drug Metabolism & Pharmacokinetics (DMPK) as well as drug discovery in general. You have expert knowledge within:

  • The drug discovery process and impact of DMPK in drug design, preferably from both small molecule project and biologics
  • PK and PK/PD modelling and translation of discovery data for delivery to pre-clinical and early clinical development
  • Transporters, Drug-Drug Interactions and their impact on drug exposure
  • PK modelling software such as Phoenix WinNonlin and GastroPlus/ Simcyp or other relevant tools
  • Drug metabolism

To succeed, you must have the courage needed to break new land, and you are not afraid of making decisions to keep up the momentum in your projects. Your structured way of working enables you to deliver high quality within agreed deadlines, and your good communication skills enable you to come through with your agenda – and at the same time contribute to a work environment characterised by constructive collaboration.

Your new department

You will join 18 scientifically skilled colleagues based at LEO’s headquarters in Ballerup Greater Copenhagen. We are responsible for in vitro and in vivo DMPK as well as bioanalysis all the way to candidate selection. We share an ambitious scientific agenda deliver innovative solutions to the benefit of patients all over the world. Our work environment is characterised by an informal and helpful atmosphere.

We look forward to receiving your application.