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Principal Investigator, Preclinical Pharmacology (non-oncology) Wilmington United States,
Posted on : 07 May 2017
Job Summary Building upon Incyte?s successful oncology pipeline, we are now expanding the Pharmacology group into non-oncology disease indications. We are seeking a motivated individual to provide scientific leadership for our non-oncology portfolio via novel target identification and compound repurposing. A successful candidate will be able to work independently to direct in vivo experiments both internally and through external collaboration. Incyte?s culture of scientific rigor necessitates a candidate with a current and broad command of immunology and a willingness to work as part of cross-functional teams. Summary of the Essential Functions of the Job Utilize innovative preclinical in vivo study designs incorporating efficacy, pharmacodynamic and pharmacokinetic readouts to answer key biological or pharmacological questions. Act as an intellectual leader to support ongoing for first-in-class and best-in-class drug discovery programs. Work with multiple CROs to accomplish experimental goals to agreed timelines. Research potential new drug targets and present to management for consideration as new drug discovery programs. Demonstrate the ability to manage multiple projects simultaneously and successfully collaborate with stakeholders from all relevant functions. Present work at internal and external scientific meetings and publish manuscripts in peer-reviewed journals Minimum Requirements Ph.D. in pharmacology, biochemistry, cell biology, molecular biology or related field plus a minimum of 4-6 years of experience in non-oncology preclinical models. Experience with in vivo models of inflammatory, metabolic or genetic diseases. Expertise in the application of cell culture, flow cytometry, functional and molecular assays essential. Prior experience using human tissue samples preferred. Excellent communication skills, self-driven, creative and a commendable publication record.
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