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Principal Investigator, Preclinical Pharmacology (non-oncology) - United States  

Company managed [?] Still accepting applications

Posted on : 07 May 2017

Project Description

Job Summary 

Building upon Incyte?s successful oncology pipeline, we are now expanding the Pharmacology group into non-oncology disease indications. We are seeking a motivated individual to provide scientific leadership for our non-oncology portfolio via novel target identification and compound repurposing. A successful candidate will be able to work independently to direct in vivo experiments both internally and through external collaboration. Incyte?s culture of scientific rigor necessitates a candidate with a current and broad command of immunology and a willingness to work as part of cross-functional teams.  

Summary of the Essential Functions of the Job

  • Utilize innovative preclinical in vivo study designs incorporating efficacy, pharmacodynamic and pharmacokinetic readouts to answer key biological or pharmacological questions.
  • Act as an intellectual leader to support ongoing for first-in-class and best-in-class drug discovery programs.
  • Work with multiple CROs to accomplish experimental goals to agreed timelines.
  • Research potential new drug targets and present to management for consideration as new drug discovery programs.
  • Demonstrate the ability to manage multiple projects simultaneously and successfully collaborate with stakeholders from all relevant functions.
  • Present work at internal and external scientific meetings and publish manuscripts in peer-reviewed journals

Minimum Requirements

  • Ph.D. in pharmacology, biochemistry, cell biology, molecular biology or related field plus a minimum of 4-6 years of experience in non-oncology preclinical models.
  • Experience with in vivo models of inflammatory, metabolic or genetic diseases.
  • Expertise in the application of cell culture, flow cytometry, functional and molecular assays essential.
  • Prior experience using human tissue samples preferred.
  • Excellent communication skills, self-driven, creative and a commendable publication record.