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Principal Investigator Discovery Research - Italy  

Company managed [?] Still accepting applications

Posted on : 03 May 2017

Project Description

Description:
We are currently seeking a Project Leader (Principal Investigator) for the Discovery Group experienced in hit identification and lead generation to drive our proprietary discovery projects.
 


 RESPONSIBILITIES: 
  In cooperation with the Director of Discovery Research, and Program Manager, defines deliverables, project plan, timelines and budget for the discovery project
  • Defines the outsourcing plan and identifies appropriate CROs or academic collaborators, negotiating costs and timelines 
  • Manages the development and execution of the project plans 
  • Addresses or reports  conflicts and project constraints 
  • Supervise objectives connected with laboratory experiments 
  • Plans, schedules and tracks progress to project milestones 
  • Ensures information and decisions are clearly communicated, documented and archived. Maintains project core files 
  • The successful candidate will be familiar with the early steps of the drug discovery process, including: functional in vitro assay generation, HTS, hit validation and the full range of hit to lead activities. 
  • He/she will coordinate all laboratory activities necessary to identify and then optimize new bio active small molecules against a defined target as potential new drugs, in collaboration with company  biologists, chemists and external collaborators. 
  • Moreover he/she will actively monitor the scientific literature on the targets and therapeutic areas of interest and the competitive landscape. 
  • The successful candidate will have a strong scientific and technical background, together with proven experience in successful early drug discovery projects in an industrial environment. 
  • The position will require the ability to work with multidisciplinary and international teams and strong communication skills with both internal and external partners.
 


QUALIFICATION & SKILLS:
  • A Ph.D. in cell biology, pharmacology or related discipline is strongly preferred. 
  • Familiarity with basic pharmacological concepts for receptors, ion channels, enzymes and transporters 
  • Familiarity with drug discovery in the area of CNS diseases would be strongly preferred 
  • Hit to Lead process including basic concepts of medicinal chemistry and in vivo pharmacokinetic studies 
  • Fluent spoken and written English 
  • Self-motivated and organised 
  • Excellent team player 
  • Ability to set and work within defined deadlines and budget 
  • Excellent analytical skills;
    • ability to address technical challenges
    • ability to process and analyze complex results and data sets 
  • Excellent interpersonal skills, ability to develop productive relationships with multiple and different parties, including scientists, scientific institutions representatives, good conflict management skills. 
  • Proficient in Microsoft Office programs (Excel, Word, PowerPoint) 


Equal opportunity employer
  • Our company  offers a stimulating work environment and a competitive salary.
  • If your background and personal experience fit this profile, please send your complete application.