Postdoctoral Researcher Investigating the Role of Phase Transitions and Stress Granule Dynamics in Neurodegeneration - Belgium
- The Laboratory of Neurobiology is part of the research group Experimental Neurology (Neuroscience Department).
- The group has a close collaboration with the Neurology Department of the University Hospitals with about 50 researchers in different domains.
- In addition, the laboratory is one of the research groups of the Center for Brain & Disease Research focusing on Neuroscience.
- There are 13 research groups within the CBD with a total employment of 230 researchers.
- The Laboratory focuses on clinical and fundamental research into the prevention, heredity, the pathogenesis and treatment of neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
- The research project will focus on the role of low complexity domains in disease-causing proteins, with a special focus on the dipeptide repeat proteins (DPRs) encoded from the hexanucleotide repeats.
- Effects of these DPRs on the nucleocytoplasmic transport and stress granule formation will be investigated.
- Biophysical techniques will be used to study the structural characteristics and dynamics of these structures.
- Moreover, this research will involve in vitro techniques including work with iPSCs, as well as in vivo research using small animal models
- We are looking for a highly motivated postdoctoral researcher with interest in neurodegeneration and experience in.
- Motivated candidates with a strong commitment to basic research are invited to apply.
- should hold a PhD degree in biology, biochemistry or biomedical sciences
- should have experience in research on neurodegenerative disorders
- should be able to work in a team with a high degree of autonomy
- should be able to guide and supervise PhD students
- should fluently speak and write English.
- We offer a fulltime 3 year contract for a postdoctoral position in an enthusiastic and motivated team and a dynamic scientific work environment.
- The Center for Brain & Disease (CBD) is an international research group focusing on neuroscience.
- The CBD provides different opportunities to present and share data on weekly seminars, lectures and international conferences.
- Different state-of-the-art core facilities are available for all CBD researchers.