BrightOwl Loader Loading

Postdoctoral Fellow, Neurodegeneration and Repair Cambridge United States,  

Biogen (company)


Posted on : 02 June 2017

Project Description

External Posting TitlePostdoctoral Fellow, Neurodegeneration and Repair
Job DescriptionThe Neurodegeneration and Repair Department at Biogen is seeking a highly motivated, creative and independent Postdoctoral Research Fellow to join Dr. Warren Hirst  lab which is responsible for bringing new targets and therapeutic strategies from discovery to development for Parkinson s disease and other movement disorders. The project will focus on the role of glial cells in the pathophysiology of Parkinson s disease. Genes known to play a causative role in the development of Parkinson s disease are expressed in astrocytes and microglia, including DJ-1, iPLA2, ATP13A2, LRRK2, GCase, PINK1 and Parkin. Emerging data suggest that these genes play important roles in glial function through their convergence on four main cellular functions; lysosomal function, lipid handling, mitochondrial health and inflammatory responses. Perturbation of these functions, by mutations in PD-genes, results in glial dysfunction, which is hypothesized to be detrimental to surrounding neurons resulting in

Locations

Cambridge, MA, US

Find a Job Find Candidates

Similar Jobs

Other jobs in United States

Other jobs in Cambridge

Other similar job in Cambridge

Other Jobs

Most Recent Searches

Most Famous Searches

You might also like