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Post Doctoral Scientist-FDE United States,  

Lilly (company)


Posted on : 22 October 2017

Project Description

36095
Post Doctoral Scientist-FDE
Greenfield
Indiana
United States
Elanco is a global research-based company that develops and delivers product and services to enhance animal health and production. We value innovation, both in scientific research and daily operations, and strive to cultivate a collaborative work environment for more than 7,000 employees worldwide. Founded in 1954, Elanco is a division of Lilly. Our worldwide headquarters and research facilities are in Greenfield, Indiana
The Post Doctoral Scientist is responsible for conducting basic and applied research as an individual contributor in the Elanco Research Labs and the Virology Research group. The primary research project will involve genetic, molecular, and structural elucidation of virus:receptor engagement. A strong foundation in molecular biology techniques and structural biology will be required to proactively search for solutions in this discovery driven team. The ability to independently conceptualize and execute experiments, coupled with a can do  attitude, is essential.

Key Objectives/Deliverables
  • Perform mutagenesis of viral cDNA clones and/or protein expression plasmids. Analyze mutation phenotypes and design follow-up experiments
  • Design and execute complex protein expression and purification strategies
  • Analyze oligomeric protein complexes from biochemical and structural perspectives
  • Participate in cross-functional research teams and effectively collaborate with other functional groups in the organization
  • Enable the timely progression of research projects through the practical application of scientific expertise which may include planning, protocol creation, hands-on laboratory work
  • Keep abreast of relevant scientific literature/new technologies /capabilities.
  • Proactively search for novel technologies or product opportunities and establish collaborations and research programs to deliver innovative technical solutions
  • Demonstrates proficiency at data reporting, interpretation, and trending.
  • Demonstrates good documentation skills with regard to raw data recording and protocol authoring
36095BR
PhD degree in virology, immunology, structural biology, molecular biology or related scientific discipline and/or M.D. or D.V.M.
Additional Skills/Preferences :

  • Broad knowledge of Virology and Molecular Biology principles including molecular cloning, PCR, Gibson Assembly, and nucleic acid extraction, purification, & sequence analysis
  • Extensive experience with viral reverse genetics including design and rescue of recombinant virus from viral molecular clones / cDNA in cell culture systems.
  • Extensive experience with protein biochemistry, including recombinant protein expression and purification and co-immunoprecipitations
  • Effective oral and written communications skills.
  • High personal ethical and quality standards.
  • Exceptional problem solving and decision-making skills.
  • Must be able to work productively in an interdisciplinary team environment
  • Experience with structural elucidation of viruses and/or oligomeric protein complexes including crystallography and/or CryoEM
  • Occasional travel (mainly US).
  • This position is not permanent. It is for a fixed duration of two years with potential to extend annually for up to 4 years.
  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Locations

Indiana, United States

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