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Monitoring neurodegeneration in the eye, the visible part of the brain - Belgium  

KU Leuven (company)


Posted on : 01 May 2017

Project Description

  • The post-doctoral researcher will have the opportunity to shape and lead a multidisciplinary research line focusing on the characterization of transgenic rodent models for optic neuropathies and neurodegenerative diseases,meanwhile supervising junior PhD students working on similar/complementary pojects (ongoing projects focus on glaucoma, Alzheimer’s and Parkinson’s disease, Wolfram syndrome).
  •  He/she should have a special interest in multimodallongitudinal invivo follow-up of disease progression andthe development of anintegrated workflow for in vivo examination of retinalneurodegeneration, inflammation and cellular stress, electrophysiological function, and behavioral read-outs ofvisual function. 
  • Using this multidisciplinary approach, in which several potential biomarkers are combined indiagnostic and prognostic models, he/she will contribute to the search for novel therapeutic approaches to halt or retard neurodegenerationin the human eye and brain. 

As an ideal applicant for this position,
  • You have a PhD in Biology, Biochemistry, Bio-engineering, Biophysics, Biomedical Sciences or equivalent and a proven and successful track record
  • You are passionate and motivated to work on ambitious projects in an open, dynamic and scientifically advanced team
  • You have a strong interest in neurobiology– ophthalmology
  •  You have good knowledge of the English language, both spoken and written
    • Basic knowledge of molecular biology is required
    • Basic knowledge of ex vivo/in vitro cell cultures is required
    • Experience with in vivo experiments inrodents is required
    • Hands-on experience with retinal imaging and/orERG analyses is an asset
    • Hands-on experience with image analysissoftware (programming) is an asset
    • Hands-on experience with proteomicsanalyses is an asset


We offer
  • An exciting working environment where quality, professionalism and humancontacts are paramount
  • The ability to work on scientifically state-of-the-art projects and provide a meaningful contribution to the development of novel biomarkers and therapeutic treatments for neurodegenerative diseases.