Posted on : 08 November 2016
Job Description: We’re offering a full time position for a Modeling and Simulation Scientist to strengthen the Pharmacokinetics Modeling & Simulation team. A Modeling and Simulation Scientist will implement modeling and simulation strategies to streamline preclinical and clinical development plans, using Pharmacokinetics, PBPK, PK/PD modeling, Disease Progression models and Clinical Trial Simulation. He/She will provide expertise in Integrative Pharmacology or applied Modeling and Simulation and will have an active role in cross-functional teams, interfacing with discovery / CMC / pharmacology / toxicology / bioanalysis / clinical. He/she will contribute to the PK/PD Modeling & Simulation components of regulatory submissions. He/she will continuously evaluate and test new technical Modeling and Simulation approaches / platforms / tools, and actively extend the PK/PD knowledge of the nanobody platform. Externally, the Modeling and Simulation Scientist will present at scientific conferences, and will be charged to keep contacts with a network of KOL’s and academics with the objective to add strategic value in the development and progression of a compound. Profile: A doctoral degree (PhD, Pharm D, MD) is preferred in Pharmacokinetics, Biostatistics or a related discipline. Experience or understanding of drug development is required. Knowledge of NONMEM and/or other Modeling and Simulation tools and programming language (e.g. R, MatLab, SAS…) is a pre-requisite. Experience with large molecules or biologics would be an advantage. Ablynx works on a wide variety of disease indications, but an expertise in one of the following would be a plus: inflammation, hematology, infectious diseases, oncology. Teamwork ability and communication skills are necessary.
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