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博士研究員メディシナルケミストリー / Medicinal Chemistry Ph.D. Researcher - Japan  

Takeda (company)

Posted on : 19 September 2017

Project Description


Our goal is to be the best in class medicinal chemistry organization to discover mainly innovative small molecule drugs for the patients. We can make an impact on patients' lives suffering from CNS and other diseases by our strength of chemistry. Let's work together to create medicines for a better health and brighter future!


The post doc proposes and conducts medicinal chemistry to advance drug discovery research in our Central Nervous System (CNS) Drug Discovery Unit. And develops compound design and creates synthesis route to ensure timely completion of generation of drug candidates by using cutting edge chemistry.


Explores small molecules and other modalities designed by oneself or one's colleagues for drug discovery projects in order to advance those programs into clinical development

Designs synthetic targets for lead discovery and optimization to address issues of target potency, selectivity, animal pharmacokinetics, toxicity, physical property and in vivo efficacy with diversified modalities (mainly small molecule)

Develops synthesis routes of molecules designed by oneself or one's colleagues to execute it

Reports to one's supervisor and shares information with one's colleagues about progress and issues in a timely manner

Collaborates closely with a broad group of scientists within Takeda, and/or with external collaborators and outside service providers as a member of project team

Addresses safety and health control / code of conduct / compliance

Education, Experience and Skills


Ph.D. in chemistry with thesis

Expertise and experimental technique of organic chemistry

Is highly knowledgeable in one's specific research area in chemistry

Is highly motivated with a strong interest in chemistry

Contributes to create an open atmosphere from diversified perspectives and challenges the status quo without hesitation

Willingness to work in a dynamic and changing environment

Manual dexterity required to operate office equipment (computers, phones, etc.)

Good communication and interpersonal skill to work in a team setting.

Addresses safety and health control / code of conduct / compliance

No allergies against any organic reagents and any solvents


Research experience in the pharmaceutical industry or academic position

General knowledge of drug discovery process

Extensive experience in large scale synthesis

High level of motivation and a proven record of accomplishment

Possesses research experience outside Japan.


English: Business level (good writing, reading and speaking skill)

Japanese: Daily communication skill is a plus

Employment Category
Contract Employee

Initial Work Location
Shonan Research Center, Fujisawa, Kanagawa, Japan

Employee Benefits

Allowances: Commutation, Housing, Overtime Work etc.

Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/Yamaguchi) 8:00-16:45, Research Site (Kanagawa) 9:00-17:45

Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)

Paid Leaves: Annual Paid Leave, Special Paid Leave, Refresh Leave, Maternity Leave, Childcare Leave, Family Nursing Leave, Philanthropy Leave.




中枢疾患創薬ユニット ドラッグディスカバリーケミストリー研究所で、医薬品の研究開発を前進させるためメディシナルケミストリーを担当して頂きます。最先端の化学を用い、化合物のデザイン及び合成ルートの立案を行い医薬品候補化合物の創出に貢献して頂きます。



























・英語: ビジネスレベル

・日本語: 日常のコミュニケーションスキルがあれば、より好ましい







・昇給・賞与: 昇給 原則年1回 賞与 年2

・勤務時間: 本社(大阪・東京)9001730 / 工場(大阪・山口)8001645 / 研究所(神奈川)9001745


・休暇: 年次有給休暇、特別有給休暇、リフレッシュ休暇、産前産後休暇、育児休暇、子の看護休暇、介護休暇、フィランソロピー休職制度