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In vitro PDM Senior Scientist & Discovery Project Team Representative Beerse Belgium,
Posted on : 26 December 2016
The senior scientist vacancy is a key scientific position within Pharmacokinetics, Dynamics and Metabolism (PDM) department, a crucial discipline of Preclinical Development and Safety within Janssen Pharmaceutica. This position is based at the Beerse site (Belgium).PDM s primary responsibility is to obtain relevant insights on processes that control ADME of small molecule drug candidates with the aim of providing a mechanistic understanding of the pharmacokinetics pharmacodynamics as well as safety novel drug candidates in patients.The PDM team in Beerse is looking for a highly motivated individual who will provide in vitro ADME support and contribute to project progression and decision making by providing expert opinion to multi-disciplinary discovery project teams. The successful candidate will play a crucial role in the mechanistic evaluation of new drug molecules to aid the early identification of development risks/opportunities within a scientific state-of-the-art and inspirational environment. The incumbent will be involved in the proposal, design and over-seeing/ execution of in vitro studies. The role will also involve interaction at the global level through science-focused working groups as well as opportunities for people managementQualificationsPhD in a relevant life science discipline and a minimum of 3-5 years post-doctoral experience in a related field.A fundamental understanding of drug discovery/development and the role of pharmacokinetics.Extensive hands-on experience in multiple in vitro ADME screening assays as well as the ability to design, supervise and interpret mechanistic in vitro ADME studies.Strong analytical thinking and proven ability to develop innovative research solutions is highly desirable and candidates with a broad lab-based experience in in vitro ADME will be given favourable consideration. Experience of LC-MS analysis is required and expertise in using/programming automated liquid handling platforms is desirable.Prior experience of representing the ADME/ DMPK field on multi-disciplinary project teams in a drug discovery environment is desirable.Evidence of active scientific participation and collaboration with colleagues in the ADME/DMPK community via scholarly publications and presentations at national/international conferences.What s in it for you &? Caring for the world, one person at a time & As an employee we consider you as our most valuable asset.
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