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Immunology-Oncology Biology Senior Scientist II / I, Immune Profiling - United States  

Company managed [?] Still accepting applications

Posted on : 22 December 2017

Project Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as an Immunology-Oncology Biology Senior Scientist II / I, Immune Profiling in our location office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Senior Scientist II / I working on the Immunology Research team, you will be empowered to support deep immunoprofiling and single-cell sorting for Immuno-Oncology programs and interpret datasets involving high-throughput genomic and immune-profiling data, and a typical day will include:

POSITION OBJECTIVES:
Based in Cambridge, MA, this research scientist will leverage a cutting-edge flow cytometry platform for support of Immuno-Oncology programs in Takeda. In addition the candidate will continue to explore and introduce new technological tools to further expand a world-class immunology group. The candidate will experimentally evaluate/explore (i) mechanisms of action, (ii) various combinatorial therapies, (iii) immune biomarkers and (iv) therapeutic response in pre-clinical setting. He/She will also contribute scientific know-how and expertise in immunology and will develop strategies, explore hypotheses and interpret datasets involving high-throughput genomic and immune-profiling data.

POSITION ACCOUNTABILITIES:
  • Reports to Assoc. Dir. Immunology/Head of Immune Profiling Immunology Unit Boston.
  • Leverages a world-class flow cytometry facility in Boston to support deep immunoprofiling and single-cell sorting for Immuno-Oncology programs through to clinical proof-of-mechanism.
  • Spends ~ 85% of time in laboratory to maintain and implement a world-class immunoprofiling platform and assist in downstream experimental assays.
  • Integrates this platform with bioinformatics and genetics approaches (including profiling approaches such as Nanostring), by leveraging internal expertise in Takeda in combination with academic partners and CROs.
  • Serves as a liaison for immunoprofiling in the Immunology Unit, establishing best practices and scientifically rigorous standards for procedures, data management, and data interpretation.
  • Assists in the identification, advancement, and success of innovative external partnerships for Immuno-Oncology.
  • Provides immunological expertise for Immuno-Oncology programs as appropriate. 
  • Plays a key role in translational research activities, including biomarker discovery and validation.
  • Keeps up with the up-to-date scientific advancement (e.g. systems approach to identify immune signatures, not limited to, T cell clonotype analysis in blood or tissues, mass spectrometry, and single-cell gene expression analysis).

EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS:

  • PhD in Immunology
  • 4-5 years postdoctoral ‘hands-on’ work carried out in world-renowned Immunology / Immuno-Oncology lab
  • Publication record in top scientific journals (International reputation)
  • Expert in high-definition flow cytometry instrumentation, assay development, and data analysis
  • Minimum 1-2 years of ‘hands-on’ experience in Industry setting with track record of contributing deep immuno-profiling support to programs and able to work well across multi-functional groups.

TRAVEL REQUIREMENTS:

  • Requires approximately 10% travel, including international

WHAT TAKEDA CAN OFFER YOU:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine


Learn more at takedajobs.com.

Takeda is an EEO employer of minorities, women, disabled, protected veterans, and considers qualified applicants with criminal histories in accordance with applicable laws. For more information, visit http://www.takeda.us/careers/EEO_Policy_Statement.aspx

No Phone Calls or Recruiters Please.

#LI-JT1


Schedule
Full-time