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Experienced Scientist in Neuroinflammation - Belgium  

UCB (company)

Posted on : 03 September 2017

Project Description


We now have an exciting opportunity in the New Medicines department at our research site in Belgium, close to Brussels (Braine l’Alleud), for  a (m/f)



Experienced Scientist in Neuroinflammation



Nature and scope


This is an exciting role for a talented neuroimmunologist to work within the Neuroinflammation Team/Neuroscience Therapeutic Area, and engage in breakthrough research in a vibrant drug discovery environment – inspired by patients, driven by science. The individual will be involved in cutting edge Neuroimmunology/Neuroinflammation-related research therefore the ideal candidate must possess the following qualities:


  • An excellent communicator, with a strong team ethic, ability to build relationships and work effectively across functions.
  • Dynamic and passionate about science and making a difference in the lives of those suffering from neurological disease.
  • Able to challenge and improve the efficiency of our way of work and the flexible to work in a fast paced environment.
  • Highly self-motivated, innovative, entrepreneurial, and driven individual
  • Strong analytical skills
  • Focused and well organized


Experience and skills:


  • A background in immunology and neuroinflammation backed by publications
  • A minimum of 3 years of post-doctoral experience required. Pharma experience highly desirable.
  • Exceptional attention to detail and a keen interest in understanding the role of glia and peripheral immunity in neurodegenerative diseases.
  • Potential to grow  into the role of pre-clinical project team leader and mentor junior scientists.
  • Excellent communication and presentation skills to represent neuroinflammation drug discovery activities at internal and external scientific meetings and academic collaborators.
  • Excellent scientific writing skills


Technical Skills:


  • Hands-on experience with human primary (healthy/patient), IPSC-derived and rodent glia and neuronal cell cultures is required.
  • Experience with AAV and CRISPR/CAS9 genetic manipulation of primary immune, glial and IPSC-derived cells and high content imaging/ flow cytometry is required.
  • Experience with immunocytochemistry of human and rodent tissues and a wider range of molecular biology techniques is required. 
  • Hands on experience  assays using CSN tissue culture/organoids highly desirable.
  • Hands on experience with animal models of neurodegenerative disease highly desirable.
  • English required, French desirable


Major Accountabilities:


The successful candidate will:

  • Engage in exciting drug discovery research including validation of novel drug targets and championing their progression through the preclinical project pipeline.
  • Work side by side (at the bench), train and mentor junior scientific staff including post-docs in the use of new technologies.
  • Work proactively across sites and functions and with external parties (contract research organizations and academic collaborators) to advance projects.
  • Represent the neuroinflammation to UCB governing bodies, various project teams, academic collaborators and scientific meetings by giving effective presentations.


Position Title and benefits commensurate with experience.

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