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ERC Funded Postdoc: Enhancer Control - Belgium  

KU Leuven (company)

Posted on : 08 March 2017

Project Description

  • You will use a combination of high-throughput techniques, including RNA-seq, ChIP-seq ATAC-seq, and massively parallel enhancer-reporter assays (MPRA) to identify and characterize enhancers in animal genomes. 
  • These data will be used to train new enhancer models  using machine learning approaches, to block enhancers using CRISPR-Cas9 techniques, and to synthesize enhancers with new functions. 
  • As model system, you will use dynamic state transitions of human cancer cells, in vitro and in vivo.

  • PhD in LifeSciences, Bio-Engineering, Biomedical Science, or similar. 
  • Strong experience or interest in gene regulation.
  • Strong molecular biology and genetics skills, including cloning (Gateway/Infusion, BAC) and CRISPR-Cas9.
  • Experience with cell culture, mouse or Drosophila genetics is a plus.
  • Experience with next-generation sequencing, transcriptomics, epigenomics and bioinformatics is also considered as a plus. 
  • Fluency in written and spoken English is required.

  • A stimulating international research environment.
  • A renewable contract.
  • Competitive salary and benefits.
  • Relocation support possible for international applicants.

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