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Discovery Toxicologist - Japan  

Takeda (company)

Posted on : 19 September 2017

Project Description

- Provide intellectual support to early drug discovery teams from a safety perspective. Design experimental plan to de-risk target and chemistry, new modality, mechanism of modulation.
- Work as core member of discovery drug project teams as the safety representative.
- As part of the Global Discovery Toxicology Team work in interdisciplinary teams within and across Global Safety to provide safety support to early discovery teams and engage in core activities within the Discovery Toxicology group.
- Work as part of a team of safety assessment scientists and more broadly DMPK, pathology, pharmacology, and medicinal chemistry experts to implement discovery toxicology strategy to enable the selection and progression of optimized drug candidates.
- Apply novel toxicity mechanism-based assays and integrated models to support early target safety and chemistry evaluation.

- Can contribute and/or lead to create new drugs from the safety point of view, "Safety by Design".
- Can have an experience of discovery toxicology similar to major pharmaceutical company.
- Can have a toxicological point of view regarding physiology / pharmacology.
- Have a chance to work with overseas colleagues through Boston and California.
- Have a chance to contribute international consortium relating to safety.

<Education, Experience and Skills>
- MS in a biomedical science with drug discovery experience (8 years) or PhD with drug discovery experience (5 years), preference Molecular Pharmacology/Toxicology, but other Biomedical Fields are also acceptable
- Requirement: Drug Project Team Experience. Applicants who are master grade, have more than 8 year-experience in pharmaceutical company, while Ph.D. grade, more than 5 year-experience.
- Desirable  : Drug Discovery Experience, Toxicology experience.
- Preferable : Experience and knowledge of bioinformatics such as pathway analysis as well as broad knowledge of Pharmacology, Physiology, Pathology, Drug metabolism, etc.
- Language: Japanese (Native), English (Business level)

Regular Employee

Shonan Research Laboratories, Fujisawa city, Kanagawa prefecture

・Allowances: Commutation, Housing, Overtime Work etc.
・Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/Yamaguchi) 8:00-16:45, Research Site (Kanagawa) 9:00-17:45
・Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)
・Paid Leaves: Annual Paid Leave, Special Paid Leave, Refresh Leave, Maternity Leave, Childcare Leave, Family Nursing Leave, Philanthropy Leave.


- 当グループはボストンやカリフォルニアなどを含むグローバル組織であり、海外サイト一緒に仕事をすることができます。
- 安全性の視点から新薬探索に貢献し、プロジェクトをリードできます。
- 欧米の大手製薬会社と同等の新薬探索を経験できます。
- 生理学や薬理学を安全性の視点から理解できるようになります。
- 海外で実施されているグローバルなコンソーシアムとも共同研究に貢献できる機会があります。









神奈川県藤沢市 湘南研究所

・昇給・賞与: 昇給 原則年1回 賞与 年2回
・勤務時間: 本社(大阪・東京)9:00~17:30 / 工場(大阪・山口)8:00~16:45 / 研究所(神奈川)9:00~17:45
・休暇: 年次有給休暇、特別有給休暇、リフレッシュ休暇、産前産後休暇、育児休暇、子の看護休暇、介護休暇、フィランソロピー休職制度