Director / Associate Director, Bioassay Group - United States
|External Posting Title||Director / Associate Director, Bioassay Group|
|Job Description||We are looking for an Associate Director/Director to lead an Assay Development and Screening Technologies group in Biogen’s Biotherapeutics and Medicinal Sciences (BTMS) Department, supporting cross-functional teams engaged in target validation, lead identification/optimization, and clinical candidate identification for neurodegeneration and additional applications.|
ESSENTIAL FUNCTIONS AND RESPONSIBILITIES:
o Lead target-based enzymology and cell-based assay development and implementation.
o Lead phenotypic screening of cell lines and induced pluripotent stem cell (iPS) by using complex image based assays and associated robotic equipment.
o Create assay development and qualification workflows for both HTS and medium throughput compound screening campaigns.
o Develop an internal vs external screening strategy and establish strong working relationships with key CROs for both HTS and routine compound screening
o Develop and implement a strategy for big-data analysis and interpretation.
|Location||Cambridge, MA, US|
|Qualifications||o Experience with high- throughput screening of neuronal and iPS cells is desirable.|
o Strong technical expertise and quantitative skills in biochemical and cell-based assay development and screening to enable small molecule/target discovery, lead identification, and optimization.
o Demonstrated leadership capabilities to develop a high performing team and drive change including a record of hiring, training, mentoring and managing of groups of scientist and managers of scientists.
STRONG COLLABORATIVE SKILLS IN WORKING WITH INTERNAL AND EXTERNAL SCIENCE AND TECHNOLOGY GROUPS:
o Collaborate with Medicinal Chemistry and Research IT to establish and strengthen relevant data workflows ranging from compound registration to LIMS for HTS and routine assay data generation and analysis.
o Establish collaborative interfaces with Therapeutic areas to execute on projects and ensure an alignment of priorities
o Effective communicator of ideas, project goals and results to team members across cross-functional roles/departments.
|Education||o PhD in cell, molecular biology, biochemistry, biophysics, or neurobiology with minimum of 10 years industry experience.|
|About Biogen||Biogen (NASDAQ: BIIB) is a biotechnology leader that discovers, develops and delivers innovative therapies for the treatment of neurodegenerative and rare diseases. Patients worldwide benefit every day from our medicines for multiple sclerosis (MS) and hemophilia. |
Founded in 1978, Biogen is one of the world’s oldest independent biotechnology companies. Our development pipeline is focused on areas of high unmet medical need, as we pursue new therapies for patients suffering from diseases with few or no treatment options. These include programs for Alzheimer’s Disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, spinal muscular atrophy and neuropathic pain amongst others.
With more than 7,000 people worldwide, Biogen is truly a global organization. We are headquartered in Cambridge, Massachusetts, which is home to our research operations. Our international operations are based in Zug, Switzerland and we have world-class manufacturing facilities in North Carolina and Denmark. We offer therapies globally through direct affiliate presence in 30 countries and a network of distribution partners in over 50 additional countries.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
Please be advised that all legitimate correspondence from a Biogen employee will come from "@biogen.com" email accounts.
Nearest Major Market: Cambridge
Nearest Secondary Market: Boston
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