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Dir. to Exec. Dir. (DOE), Immuno-oncology Biotherapeutic Antibodies - Preclinical - United States  

Company managed [?] Still accepting applications

Posted on : 07 May 2017

Project Description

We are seeking a highly motivated and experienced individual with an understanding of biotherapeutic drug development to join our immuno-oncology discovery team at Incyte, Wilmington, DE. This position is responsible for building and leading a team of scientists to support the preclinical biology efforts for immuno-oncology biotherapeutic antibody drug discovery programs. The successful candidate will have a strong scientific background in immunology and/or oncology, and experience in drug discovery. The successful candidate will directly contribute to target identification, validation, characterization, and selection of antibody-based cancer immunotherapeutics. A demonstrated track record of utilizing their knowledge to design and execute a research strategy that answers pivotal questions about the novel targets or biology under evaluation is required.

Job Responsibilities:

  • Maintains an excellent grasp on emerging areas of immuno-oncology research and new therapeutic targets
  • Develops pharmacological strategies and implements experimental approaches for addressing key scientific questions in each of the antibody programs
  • Plays a visible role in decision-making process on cross-functional antibody discovery teams, providing core expertise and input on scientific direction
  • Ensures generation of high quality data to support decision making on individual programs and effectively communicates the data to senior leadership
  • Leverages external collaborations to generate key pharmacological data in support of discovery programs
  • Advocates early development strategy, biomarker selection, and combination approaches for new development programs
  • Maintains strategic focus across multiple complex drug discovery projects in prioritizing resource allocation to drive decisions consistent with the corporate goals
  • Effectively collaborates with other functions in the discovery and clinical departments
  • Manages Pharmacology personnel (Ph.D and BS/MS level scientists) including development, mentoring, and effective delegation

Minimum Requirements:

  • Ph.D. in Immunology, Pharmacology, Cancer Biology or related field
  • Post-doctoral experience in a relevant field
  • 5-10+ years of pharmaceutical or biotech experience
  • Supervisory and research team leadership experience
  • Excellent communication skills and a solid publication record