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Biologist-Incretin Discovery - United States  

Lilly (company)

Posted on : 07 May 2017

Project Description

Biologist-Incretin Discovery
United States
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
The Lilly Diabetes and Complications Research organization has created a research team focused on discovery and preclinical development of new therapeutics in the area of Incretin Discovery. The Incretin Discovery team is looking for an experienced in vitro biologist to develop, validate and conduct in vitro and cell-based pharmacology assays for diabetes drug discovery projects. The candidate should have a proven track record in the implementation of in vitro assays and be able to consistently follow detailed protocols and provide critical and thorough data evaluation. The candidate is expected to work in collaboration with the Incretin and Insulin Discovery groups in a team-oriented environment and to support other groups in the Diabetes and Complications Therapeutic Area with expertise as needed.
  • Design, validate and implement in vitro assays for novel incretin therapeutics. Critically evaluate data and troubleshoot.
  • Perform cell culturing and molecular biology/biochemistry techniques, including cell line generation and evaluation.
  • Develop and perform assays in the area of receptor pharmacology including receptor binding, GTPγS binding, and functional assays in cells, such as cAMP, phosphorylation, and metabolic readouts.
  • Requirement for accurate record keeping, independent data analysis, and reporting of data in written and oral formats. Perform work in full compliance with Lilly Research Policies, and complete all required training activities in the timeframe specified.
  • Ability to be pro-active, flexible and capable of independent trouble shooting and problem solving.
  • Bachelor's Degree in biology or a closely related field with 3+ years of laboratory research experience or Master’s degree with research in a related area
  • Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position.
  • Experience in developing, running and evaluating data from in vitro assays, such as receptor binding, functional assays in cells, ELISAs, SDS-PAGE gels and western blotting
  • Experience with assay automation to enable compound screening is preferred.
  • Experience and willingness to work with radioisotopes, chemical, and biological hazards.
  • Experience in diabetes and/or metabolic diseases is preferred.
  • Proven ability to work in flexible, team-oriented environment.
  • Oral/written communication/listening skills in English are essential.

  • The position level will be commensurate with the candidate’s experience. The position is governed by regulations including OSHA, AAALAC, OLAW and NRC — compliance to all applicable regulations is mandatory.

  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.