BrightOwl Loader Loading

Associate Scientist, Upstream Process Development - United States  

MSD (company)


Posted on : 04 June 2017

Project Description

  • Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. 
  • The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where our company  has codified its 125-year legacy. 
  • Our company’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
  • Our company is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. 
  • Today, we’re doubling down on this goal. Our Research Laboratories is a true scientific research facility of tomorrow, and will take our company’s leading discovery capabilities and world-class small molecule and biologic R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.
  • Applications are sought for a scientific opportunity in MRL Vaccine Bio-process Research and Development.  
  • Under the direction of the group leader, individual will be responsible for upstream process development of vaccine candidates. 
  •  The successful candidate will perform lab-scale process development/scale-up studies, develop robust, efficient, scalable cell culture processes for vaccine production, participate in the manufacture of cGMP clinical bulks, and transfer processes to clinical or commercial manufacturing facilities for vaccine candidates.  Duties may include: lab scale fermentation, cell culture, and/or bio-conjugation process development, in-process assay support, process scale-up and engineering, cGMP document preparation and modifications, maintaining/coordinating raw material, and equipment inventories, technology transfer to manufacturing, and functioning as a key member of a process development team.
  • Individual is expected to function in a multi-disciplinary environment and to contribute subject matter expertise to various functional teams engaged in development of the vaccine candidate. 
  • The successful candidate will be expected to demonstrate the ability to communicate results of his/her work in both verbal and written formats. 
  •  In addition to the core responsibilities outlined above, the candidate will be expected to keep careful notes, comply with all required training, and maintain a focused attention on laboratory safety for himself and his team
  • Position requires employee to be willing to work with infectious agents and/or pathogens.Travel may be required to support technology transfer. 
  • This position will require occasional off hour and weekend work.

Must have a Bachelor's Degree in Engineering or Biological Sciences.

  • Must have the ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude.
  •  Must have ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.
  •  Proven ability to work in hands-on laboratory setting.
  •  Excellent organization, interpersonal, verbal and written communication skills

  • Direct experience with cell culture/fermentation, upstream process development or expression system development for vaccines and/or biologics is strongly preferred.
  • Experience working with viral systems within a BSL-2 environment.

Travel: Yes, 5 % of the Time

Number of Openings: 2
Job Segment:  Scientific, Scientist, Biology, Medical, Laboratory, Engineering, Science, Healthcare