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Associate Scientist – in vitro biology  

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Posted on : 05 April 2017

Project Description

Associate Scientist – in vitro biology

Are you an in vitro assay scientist and do you truly enjoy hands-on work in the lab?

If you like to work with in vitro pharmacological assays, and you are looking for a position where you are able to combine scientific tasks with hands-on laboratory work, this may just be the perfect job for you. You will get the opportunity to work in a successful global company and use your scientific expertise to directly influence the selection of future drug compounds by establishing, performing and interpreting data from in vitro assays for screening and characterization of new small molecule drugs within our research projects. 

Plan and execute in vitro pharmacological assay tasks

Your focus will be to plan and execute in vitro pharmacological assay tasks across a range of assay types, cell types and assay purposes. You will develop new assays as well as run existing assays within on-going LEO projects – taking responsibility for the scientific and the laboratory-based aspects of your assays. As part of the scientist group in our department, you will participate in scientific discussions and knowledge sharing across our assay tasks and projects. Your tasks will include to:

  • Establish new in vitro assays to be used in compound screening and/or compound mode-of-action characterization
  • Use automation equipment and liquid handling robotics to optimise compound throughput within assays
  • Independently design and perform own laboratory work – including data analysis and reporting
  • Provide input and ideas for new assays, methods, optimization possibilities and assay quality improvement.
  • Participate in project sub-teams and provide in vitro assay expertise in these
  • Present science and data at department or cross-functional meetings within the Skin Research area 

Strong experience in establishing cellular and biochemical vitro assays

You are a newly graduated Ph.D. or postdoc in biology, pharmacology, biochemistry or a related field. Alternatively, you bring a M.Sc. degree (or equivalent) in one of the above-mentioned fields with at least 5 years’ of experience from working in a similar role in a pharma/biotech setting.

Regardless of your background, you must bring strong experience in establishing cellular and biochemical in vitro assays for determination of compound potency and efficacy, and you see assay automation as an exciting and natural part of establishing new assays. Your experience includes in vitro pharmacological data analysis and application of assay QC criteria, including use of data analysis programs such as XL-fit and GraphPad Prism. Additionally, you have broad insight into techniques such as reporter gene assays, kinase assays, cell proliferation assays and cytokine measurements. Previous experience with isolation and culture of blood cells will be regarded as an advantage.

To succeed, you must thrive on generating and interpreting data as well as continuously seeking innovative solutions to assay technical challenges and project specific assay needs. You must like to work independently in the lab and at the same time be part of a team where helpfulness, knowledge sharing and mutual respect are key virtues. Additionally, you have the customer orientation and people skills needed to be part of a team with many stakeholders across the R&D projects.

Your new department

You will join a department with 15 skilled and dedicated scientists and lab technicians working with in vitro and ex vivo assays to support projects across the R&D area. You can look forward to being part of a team that shares your professional passion and where engaging in scientific discussions is an important part of our working day. We believe that work can also be fun, and we treasure an open and collaborative working environment. As such, knowledge sharing and helpfulness is a part of our DNA and an important foundation for being successful in our tasks.

We look forward to receiving your application.