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Associate Scientist III, Neurology & Immunology In-Vitro/In-Vivo Cambridge United States,  

Posted on : 17 April 2017

Project Description

External Posting TitleAssociate Scientist III, Neurology & Immunology In-Vitro/In-Vivo Job DescriptionThe Biogen Department of Neuro/Immunology seeks a highly motivated and keen associate scientist whose primary responsibility is to advance target validation, drug discovery and development. The individual is expected to have mastered a broad range of experimental techniques, preferably having established expertise in the field of neuroimmunology. The individual will be expected to perform with significant independence with respect to designing and executing controlled experiments, analyzing and interpreting results, establishing and executing existing or new protocols/methodologies and recommending modifications. The individual is expected to read pertinent literature and exhibit knowledge of molecular and biological processes, applying their knowledge to propose new ideas and regularly make suggestions for creative solutions to technical challenges. The individual is expected to have strong written and verbal communication skills, preparing and delivering oral presentations, posters, draft research reports and contributing to manuscripts.Responsibilities include:•Driving target validation efforts for neurodegenerative diseases such as Alzheimer s, Parkinson s and ALS, with a particular focus on glial cells and neuroinflammation.•Using a wide array of techniques relevant to neuroimmunology and glial cells•Leveraging animal models of neuroinflammation and neurodegeneration to demonstrate proof-of-biology; knowledge and experience with such models is preferred.•Designing and executing experimental plans, performing rigorous analysis and interpretation of experiments. •Collaborating with relevant individuals and groups to advance projects; demonstrating good lab citizenship.• Skilled experimentation encompassing a wide array of in vitro and in vivo techniques; relatively independent design, execution, analysis and interpretation of experiments.• Strong oral and written presentation of technical work• Collaboration with relevant individuals and groups to advance projects; demonstration of good lab citizenship.*LI-SRC6 LocationCambridge, MA, US Job CategoryResearch Requisition Number29728BR Qualifications• A wide array of in vivo experience in neurology is required. Experience with models of inflammation is also highly desirable. (Trained in IV, IP, SC, techniques)• Prior experience with stereotaxic surgery in mice or rat models is strongly preferred.• Prior experience with glial and myeloid cells, their isolation and purification from brain tissue, and assays relevant to this cell type is preferred• Cellular biology techniques such as organotypic brain slice cultures, ex vivo culturing of primary cells, iPSC cell differentiation, transient transfection, viral mediated transduction, and multicolor flow cytometry are strongly preferred.• Molecular biology techniques such as RNA isolation, qPCR, Nanostring, NGS, and protein analytical techniques such as multiplexed cytokine profiling, Western, IHC, and IF are strongly preferred.• A solid background in neuroimmunology with knowledge or experience in innate immunity is preferred.• Excellent communication and collaboration skills are required EducationA B.S / M.S degree with 5-10 years of experience in related neuroimmunology research. About BiogenBiogen (NASDAQ: BIIB) is a biotechnology leader that discovers, develops and delivers innovative therapies for the treatment of neurodegenerative and rare diseases. Patients worldwide benefit every day from our medicines for multiple sclerosis (MS) and hemophilia. Founded in 1978, Biogen is one of the world s oldest independent biotechnology companies. Our development pipeline is focused on areas of high unmet medical need, as we pursue new therapies for patients suffering from diseases with few or no treatment options. These include programs for Alzheimer s Disease, amyotrophic lateral sclerosis (ALS), Parkinson s disease, spinal muscular atrophy and neuropathic pain amongst others. With more than 7,000 people worldwide, Biogen is truly a global organization. We are headquartered in Cambridge, Massachusetts, which is home to our research operations. Our international operations are based in Zug, Switzerland and we have world-class manufacturing facilities in North Carolina and Denmark. We offer therapies globally through direct affiliate presence in 30 countries and a network of distribution partners in over 50 additional countries. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States. Please be advised that all legitimate correspondence from a Biogen employee will come from "" email accounts. Nearest Major Market: Cambridge Nearest Secondary Market: Boston Job Segment: Biotech, Scientific, Scientist, Telecommunications, Telecom, Science, Engineering, Technology


Cambridge, MA, US

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