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Associate Scientist II, Technical Development Cambridge United States,  

Biogen (company)

Posted on : 24 June 2017

Project Description

Job Description
  • Our company  is looking for a highly motivated process chemist ready to function in a fast-paced and collaborative environment. 
  • Involved in process development, scale-up, purification and characterization of small molecules to support advancement of our company s small molecule pipeline. 

  • Work with a Scientist to design synthetic organic experiments, perform them independently and efficiently to develop scalable process with the goal to tech transfer to a commercial site. 
  •  Understanding of process overview (upstream and downstream) and understands the role of critical parameters in technology transfer.
  • Closely monitor reactions in automated reactor platforms using a variety of analytical techniques and identify critical reaction variables to have impact on scalability and purification.
  • Develop efficient purification method including workup, distillation and crystallization.
  • Able to meet aggressive process development and production timeline.
  • Author process research reports and present scientific findings 
  • Maintains an electronic laboratory notebook. 

  • Have good interpersonal, communication, writing and presentation skills.
  •  Have a collaborative mindset and be able to work as part of a team.
  • Excellent knowledge of reaction mechanism.
  • Demonstrated knowledge of multi-step synthetic organic chemistry.
  •  Hands on experience with instrumental analysis using TLC, NMR, HPLC, LCMS, GC and KF.
  • Experience with a broad range of synthetic and purification techniques.
  • Have experience with Microsoft Office products; experience with ChemDraw. 
  •  Knowledge and experience with PAT technology (React IR, FBRM, PVM) 
  • Knowledge and experience with statistical software (JMP, Design Expert) 
  • Knowledge and experience with flow chemistry. 

  •  MS in synthetic organic chemistry with 0-2 yrs experience.
  •  Industrial or academic internship experience required in the pharmaceutical industry. 

About Us 
  •  Through cutting-edge science and medicine, our company discovers, develops and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. 
  • Our company  is a pioneer in biotechnology and today the Company has the leading portfolio of medicines to treat multiple sclerosis (MS), has introduced the first and only approved treatment for spinal muscular atrophy, and is at the forefront of neurology research for conditions including Alzheimer s disease, Parkinson s disease and amyotrophic lateral sclerosis (ALS).  
  • Our company  also manufactures and commercializes biosimilars of advanced biologics.   
  • Our global organization of nearly 7,000 employees is committed to a single mission: making a meaningful difference in the lives of patients with few or no treatment options.  
  • Our company  was founded in 1978 and today serves patients in nearly 70 countries.  
Our Science 
  •  We aspire to have the greatest impact on patients and science of any biotechnology company in the history of our industry.  
  • To us, that means creating novel medicines that benefit individuals and society, and bringing new scientific understanding to diseases for which there are no adequate treatments.  
  • For nearly two decades our company has led in the research and development of new therapies to treat MS, including the most prescribed oral treatment in the world. 
  •  Now our research is driving revolutionary new MS treatments with the goal of reversing or even repairing damage caused by the disease. 
  • We are now applying our neurological expertise to solve some of most challenging and complex diseases of the brain, including Alzheimer s disease, Parkinson s disease, and ALS. 
  • As we uncover new insights into human biology, our company is employing cutting-edge technologies to discover potential treatments for rare and genetic disorders.  
  • Our company  is revolutionizing biologic manufacturing, developing the industry s most advanced plants and processes. 
  •  This expertise is used to produce both original innovative therapies and bio similar that expand patient access to lower-cost medicines.  
Our Corporate Citizenship 
  •  The same intellectual discipline and passion that drives our science is reflected in our corporate citizenship, environmental sustainability, and commitment to diversity and inclusion. 
  •  As a company, we are focused on improving science education and limiting the impact of our company on the environment. 
Job Segment:  Chemistry, Scientific, Developer, Biotech, Scientist, Science, Engineering, Technology                       


Cambridge MA US

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