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Assistant Professor in Bioinformatics in the Porse Group at the Finsen Laboratory/BRIC, University of Copenhagen København Denmark,  

Posted on : 23 April 2017

Project Description

An exciting position as an assistant professor with focus on normal and malignant hematopoiesis is available in the Porse Group, at the Finsen Laboratory/Biotech Research and Innovation Centre (BRIC) in Copenhagen. We are seeking an innovative, independent PhD level computational biologist to join a group that generates omics data using the latest technologies (RNA-seq, single cell RNA-seq, ChIP-seq, proteomics) and has expertise in expression profiling, machine learning, epigenetics, visualisation and next generation sequencing data. Our research/The GroupSeveral cancers, including acute myeloid leukemias (AML), are maintained by Cancer Stem Cells (CSCs). Similar to normal stem cells, CSCs are able to self-renew and are thus the cells that need to be targeted in order to efficiently eradicate the disease. The focus of the Porse group is therefore to study cancer from a stem-cell centric viewpoint. Specifically, we address the molecular mechanisms governing both normal and malignant hematopoiesis with the aim to identify novel targets for future therapeutic intervention in patients suffering from AML Key publications relevant for computational biologists:Paul F et al., Cell 2015, 163, 1663-77Pundhir S, Nucleic Acids Research 2016, 44, 4037-51Bagger FO et al., Nucleic Acids Research 2016, 44, D917-24Rapin N. et al., Blood 2014, 123, 894-904Vitting-Seerup K et al., BMC Bioinformatics 2014, 15, 81Jakobsen JS et al., Genome Research 2013, 23, 592-603Weischenfeldt J. et al, Genome Biology 2012, 13, R35 Project/The research project(s)The successful candidate will join our bioinformatics team, currently consisting of two persons. Your time will be shared between involvement/support in projects originating from our wet lab and own projects, on which you can dedicate 20-30% of your time. You will be expected to come up with you own computational research questions and publish your results in peer-reviewed academic journals. Start: Preferably January 2018 or after agreementDuration: Two years, with a possibility for extension QualificationsWe expect you to be a highly motivated and highly ambitious scientist with the following qualifications: A PhD in bioinformatics or computational biology with 3-4 year post-doctoral experience. Experience in developing cutting-edge computational methods for next-generation sequencing (NGS) data analysis documented in the form of first author peer-reviewed research articles. Experience in integrated analysis of diverse NGS datasets documented in the form of first author peer-reviewed research articles. Strong programming skills in Perl/Python, Shell, C/C++ and statistical skills in R programming language. Ability to grasp complex problems and deliver creative, practical solutions. Strong communication and collaboration skills, including the ability to work well in a diverse academic setting, and to balance scientific and day-to-day needs. Ability to work in a team of multidisciplinary scientists, and operate effectively in a matrix environment; team player yet able to work independently with minimal direction. Excellent English skills written and spoken Preferred Experience and Skills  Experience with cluster and/or cloud-based computing environments. Strong background in molecular biology and genetics, especially related to disease and drug development will be considered an advantage. For further information regarding the position, please contact Professor Bo Porse by email at Place of employmentThe employment is at BRIC, University of Copenhagen. BRIC is located in the Biocenter, close to the centre of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD and our own Postdoc Career Programme. BRIC actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions Please read more about the Porse research group and BRIC on Terms of salary and employmentSalary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary starts at 32.351 DKK/ca. 4.250 Euro plus pension. Depending on qualifications, a higher salary may be negotiated. Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years. The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013. ApplicationYour application must be submitted electronically by clicking ‘Apply now’ below or via BRIC’s website on The application must include the following documents/attachments – all in PDF format:   Motivated letter of application (max. one page). CV incl. education, work/research experience, language skills and other skills relevant for the position. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do. List of publications. Letters of recommendationFurthermore, the applicant should provide two letters of recommendation. To be taken into consideration, the letter must be signed by the supporting person on paper with institutional letter head and in PDF-format. The letters should be received before deadline on with subject “candidate name- bioinformatics-assistantprof-Porse-2017”; preferably by the supporting person. Please make sure that an easy match between the recommendation letter and the individual applicant is possible. Application deadline: 4 May 2017 We reserve the right not to consider material received after the deadline, and not to consider applications or letters of recommendation that do not live up to the above-mentioned requirements. The further processShortlist: After expiry of the application deadline, the superior with power to appoint selects a number of applicants for assessment on the advice of the Appointments Committee. All applicants are immediately notified whether their application has been passed for assessment. Applicants who were not passed for assessment should not expect further with regard to their application unless the shortlist is revised. Assessment: The selected applications will be assessed according to the Ministry Order on the Appointment of Academic Staff at Universities 2012 and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritized assessment of the academic qualifications and experience with respect to the above mentioned area of research, techniques, skills and other requirements listed in the advertisement. You can read about the recruitment process at BRIC and University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.


1165 København, Denmark

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