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Experiences

Current Experience

  • Process improvement Manager/Scientist for GSK
    Since October 2013
    At GSK' I'm working as a support for 2 buildings of production and my mission is to implement a new single use technology into Viral and vaccine processes, in collaboration with Denmark and US. Project management & scientist activities as: - Constitution of a project team - Coordination of the project between Belgium, US and Denmark - Strong interactions with legal, intellectual property and financial stakeholders - Coordination of activities between Production and R&D services onsite - Management and installation of a new laboratory onsite and lead of experiments (Orders, supply chain, coordination) - Training and supervising new team members or more junior staff - Planning, carrying out and supervising process trials at small scale; - Write test protocols/reports, procedures, SOP’s, URS, risk assessments - Validation of single use technologies - Evaluate existing processes to identify areas for improvement - Support in defining critical process parameters, set specification and control to ensure quality is maintained - Generating data to demonstrate comparability, safety and efficacy of the products in consultation with other functions, - Improving yields by reducing costs

Past Experience

  • Process Development Scientist, Bioprocess R&D Department, Upstream platform
    March 2012 --- August 2013
    Management of project: - Supported, developed and implemented novel technologies for a transition between phases 1 & 2 of a vaccine - Managed a transfer of a technique between 2 different countries - Managed a schedule, delays and counstraints - Interacted with internal and external collaborators Process Development: - Developed a new cell line for high throughput screening of supplements (transfections, cloning, cell banking) - Optimized a serum free culture medium for DNA-virus production within Vero cells on microcarriers - Executed small and medium scale experiments in shake flasks, spinners and bioreactors up to 50L (Millipore, Dasgip) Analytical: - Plaque assay analytical technique

  • Internship Sanofi Pasteur -Bioprocessing R&D Dpt, Upstream platform-
    January 2011 --- December 2011
    Management of project: - Developed a RT-qPCR, generating my own samples in Bioreactors - Planned and scheduled the experiments - Respected deadlines - Negociated with internal and external collaborators and suppliers - Presented results Process development: - Optimized a serum free culture medium for rabies virus production within Vero cells - Cultured and Infected cells on microcarriers in different bioreactors up to 8L - Assessed a new model lab scale single use bioreactor for process development Analytical: - Developed a RT-qPCR in process monitoring tool - Analyzed Gene expression - Worked on RNA chips

  • Internship MERIAL; BioAnalytical Development Dept - PCR platform
    January 2010 --- September 2010
    Analytical: - Developed of a qPCR that replaced the reference analytical technique for canarypox virus titration on cells (DICC50) - Cloning, DNA/ARN isolation (manual, in plates) - CCID50 technique Quality - Editited procedures - Stability studies - Validated a technique - Redacted Validation, Correlation and stability reports Additional - Trained and qualified technicians - Worked in P2 environment

Knowledge

LinkedIn Assessment :
BiotechnologyCell Culturemolecular biologyMammalian Cell CultureVirologyBioreactordisposable bioreactorBioprocess DevelopmentVaccinesUpstream processingMultiplex PCRPCR primer designCloningBioprocessingR&D

Education

  • Master R&D Biotechs in Biotechnologies from Université Pierre et Marie Curie (Paris VI) in 2011
  • ESSEP 3 in Biotechnologies from Université catholique de Lyon in 2010
  • licence in Biologie Cellulaire et Physiologie from Université Jean Monnet Saint-Etienne in 2009

Area / Region

Belgique

Others

Driving License
  • No