BrightOwl Loader Loading

Experiences

Current Experience

  • Technical Leader

    Donstiennes, Thuin, Belgium
    Since June 2015
    • Quality Control of raw materials ensuring that specifications and protocols are met

    • stability studies of active Pharmaceutical ingredients and drug products

    • development, Qualification and Validation of Analytical methods following customers needs and according to the compendial regulations (ich, usp, eur.pharm)

    • review and approval of specifications, protocols, methods and reports

    • handle change requests and investigate out of specification/trend results

    • coordinate studies between customers and Laboratory, preparation of practical work

    • contribute to audit as technical Expert

    • people management, handing out/organisation of workload, conduct appraisals of team members (5 people)

     

    • Quality control of raw materials ensuring that specifications and protocols are met

    • Stability studies of Active Pharmaceutical ingredients and drug Products

    • Development, qualification and validation of analytical methods following customers needs and according to the compendial regulations (ICH, USP, Eur.Pharm)

    • Review and approval of specifications, protocols, methods and reports

    • Handle change requests and investigate out of specification/trend results

    • Coordinate studies between customers and laboratory, preparation of practical work

    • Contribute to audit as technical expert

    • People management, handing out/organisation of workload, conduct appraisals of team members (5 people)

     

Past Experience

  • Senior scientist in physical chemistry Braine-l'Alleud, Belgium

    January 2006 --- March 2015
    • coordinate and supervise activities within the physical chemistry Laboratory

    • perform Analysis on Research and development compounds (pka, thermodynamic solubility, kinetic solubility, stability, lipophilicity, polarimetry)

    • responsible for providing quality data and writing of protocols and reports

    • interpret results with a strong analytical mindset

    • implement and follow-up of new Lab processes increasing throughput and reducing cycle times

    • propose and implement various technologies in line with project needs and Strategy

    • contribute to Medicinal Chemistry projects by delivering solutions in a timely fashion

    • train and mentor Laboratory staff in a variety of Analytical techniques and supervise Student dissertations

     

  • Research scientist in solid states Braine-l'Alleud, Belgium

    September 2001 --- January 2006

    main job purpose:

     

    • participate to solid states Characterization by providing and analyzing experimental data

     

    duties and responsibilities:

     

    • growing of single-crystal for x-ray measurement, use of different technologies to answer specific question such as ‘enantiomeric’ attribution, crystal packing, h-bonding, position of ionization

    • Characterization of solid states of compounds in Research and development (crystal shape, polymorphism, 3d configuration, determination of conformation,…) and writing of internal memo

    • providing in-house crystallographic and calorimetric analyses to support salt selection, polymorphism studies, synthetic route selection

    • managing the collaboration and financial aspects with the fundp regarding x-ray powder diffraction and single-crystal x-ray diffraction

    • achieving of the first co-crystal within ucb

    • development of 'kibron' technology (determinatin of critical micellear concentration), Automation of measurement with electro mechanic team

  • Responsible for quality control Braine-l'Alleud, Belgium

    August 2000 --- September 2001

    main job purpose:

     

     

    duties and responsibilities:

     

    • responsible of the Quality Control raw materials release and of a team of 7 people

    • review/Validation of Laboratory results for release and approval of raw materials batches

    • capacity management of the raw materials qc team

    • working under GMP standard (european pharmacopeia & usp)

    • review and approval of GMP Documentation

    • settle out-of specification results

     

  • Formulation chemist Louvain-la-Neuve, Ottignies-Louvain-la-Neuve, Belgium

    April 1999 --- July 2000

    main job purpose:

     

     

    duties and responsibilities:

     

    • provide Technical Support in developing new formulated products of herbicides to be commercialized in the europe/africa regions

    • preparation of different Formulations and selection of best procedures (milling methodology, mixture,..) & composition (excipient, anti-foaming agent, …)

    • Characterization of the Formulation by physico-chemical Testing following standards operating procedures and methods available in the Lab. work under Good Laboratory Practice standard

     

  • Research and teaching responsibility Namur, Belgium

    January 1996 --- March 1999

     

    • Teaching assistant: overseeing practical Chemistry and experimental Laboratory activities

    • partnership with ‘synthelabo’ Research aiming for the implementation of a database describing molecular similarity of functional groups

    • collaboration with ucb pharma : lipophilicity scale study (logp, log kiam, log kw) of triazine compounds

     

Knowledge

Self Assessment :
Current Good Manufacturing Practice (CGMP)Analytical ChemistryDrug DiscoveryDrug DevelopmentAnalytical Method ValidationQuality AuditingFormulationsolid statesPhysical ChemistryICHGLP hit finding

Education

  • Master in Chemistry from FUNDP in 1996

Training and Certification

  • prince II foundation in 2015 Certification

Languages

BrightOwl Assessment:
Self Assessment:
French
Native
English
Professional Proficiency
Dutch
Elementary Proficiency

Area / Region

Belgium

Others

Driving License
  • Yes

Similar Candidates

Other Candidates in Belgium

Other similar Candidates in this location (country / city)

Other Candidates

Most Recent Searches

Most Famous Searches

You might also like