Team Leader, Discovery Sciences, Oncology and Neuroscience
Since August 2015
Research Laboratory Head
October 2010 --- July 2015
Research Laboratory Head at Boehringer-Ingelheim leading a team of motivated and highly-skilled scientists to strategically identify and validate novel targets for Oncology. Successfully led innovative projects from target identification/validation to preclinical development. Project management with CRO. Fostered Boehringer-Ingelheim collaboration network with academic institutions and biotech companies. Acted as chair of the Boehringer-Ingelheim internal working groups to ensure best practice in projects. Recognized with Boehringer-Ingelheim Silver Award 2013 for important contribution to discover innovative drugs for cancer patients
March 2006 --- November 2010
Post-doctoral fellow working on the study of the regulation of NADPH oxidase-1 (Nox1) activity: i) Made use of HTS technology for the identification of potent and specific inhibitor of Nox1 (results published in a first-authored article in ACS Chem Biol (2010) and summarized in two Probe Reports to the NIH (2010) ii) Successfully led other research projects resulting in three first-authored papers in peer-reviewed journals and featured in “News and Views” (see Publication list) iii) High familiarity with 2D/3D proliferation and reporter assays relevant for Oncology iv) Trained and mentored several undergraduate and graduate students, who are now pursuing their independent research careers.
May 2003 --- November 2006
Visiting PhD student in the lab of Professor Michael Geoff Rosenfeld interested in the elucidation of epigenetic mechanisms implicated in the pathogenesis of Alzheimer´s disease. Results from these studies were summarizied in a publication in EMBO Reports (2006)
November 2001 --- November 2006
PhD student working on the regulation of the cleavage of the amyloid-precursor protein (APP): i) Generated a cellular model system to identify small molecule or growth factors responsible for the proteolytic cleavage of APP. ii) Mastered molecular and cellular biology techniques for generation of stable and inducible clones. iii) Results of this research project have been published in a first-authored publication.
Certificate Program in Drug Discovery and Development from University of California, San Diego in 2009
PhD in Genetics from Università degli Studi di Napoli 'Federico II' in 2005