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Summary

I’m a PhD-level scientist with a solid background in immunology, molecular biology and antibody discovery. It is my ambition to work for an innovative (bio)pharmaceutical company and contribute to the development of new medicines. I’m a hard working person with a ‘can do’ mentality, result-oriented, eager to learn and always focused on improvement. I have a critical mindset, a keen eye for detail and good problem solving skills. I’m looking for a challenging position that gives me the chance to apply my skills and to enhance my professional experience.

Experiences

Current Experience

  • Scientist Agrobody Discovery Zwijnaarde
    Since May 2015

    • Generation of single domain antibodies (Agrobodies) against fungal targets
    • Development of new assays for the characterization of Agrobodies

Past Experience

  • Technical-Regulatory Writer and pharmaceutical consultant Mariakerke, Ghent, Belgium
    May 2014 --- May 2015

    • Writing of CMC technical documents and regulatory reports (IMPDs, Variations…)
    • Managing of multiple supplier qualification projects for a major pharmaceutical company: follow-up of CRO work, interpreting research data, writing reports, follow-up of review/approval using DocSpace

  • Postdoctoral researcher Merelbeke, Belgium
    May 2009 --- May 2013

    • Project: Generation of antibodies and nanobodies against macrophage receptor CD169 (Sialoadhesin) - Construction of fusion proteins for targeting antigens and toxins to macrophages (IWT-SBO project ‘SialoTarg’)
    • Tasks: laboratory work, data analysis, setting up and optimization of protocols,  supervision of 2 technicians, guiding master students, presenting data, writing progress reports for IWT, communication with project partners

  • Postdoctoral researcher at VUB, Diabetes Research Center Jette, Belgium
    October 2006 --- December 2008

    Overexpression of transcription factor E2F1 in beta cells to induce their in vitro proliferation

  • PhD student Ghent, Belgium
    October 2001 --- July 2006
    Overexpression and silencing of selected genes in hematopoietic stem cells and study of their differentiation capacity in in vitro and in vivo differentiation models - Microarray analysis to compare the gene expression between successive stages of blood cell differentiation

  • R&D Scientist
    September 2000 --- August 2001
    Cloning and sequencing of genes from several Diptera species, aimed at the development of biological control agents - Transformation of alfalfa and tobacco plant with TMOF (Trypsin Modulating Oöstatic Factor)

Personality

Self Assessment :
Analytical thinkingAttention to detailCreative thinkingCritical thinkingFlexibilityProblem solvingResponsibilityResult OrientedTrust

Knowledge

Self Assessment :
R&D Scientific writingAntibodiesAseptic TechniquesAssay developmentCell Based AssaysCell CultureCMC Regulatory AffairsConfocal MicroscopyDNA extractionELISAFACSGraphPad PrismImmunoassaysImmunocytochemistry (ICC)ImmunologyMammalian Cell Culturemolecular biologyPCRProblem SolvingqPCRReport WritingScientific WritingSDS-PAGEStem CellsT cellsTransfectionWestern Blotting
LinkedIn Assessment :
In VitroAntibodiesProtein ExpressionCell biologyqPCRConfocal MicroscopyImmunologyCell Culturemolecular biologyELISAFluorescence MicroscopyWestern BlottingFlow CytometryTransfectionVirologyImmunofluorescenceMonoclonal AntibodiesMolecular CloningCell

Skills and Expertise

Self Assessment :
Guide students Report data Write papers Write protocolsCell culturecollaborate in research projects at universitiesCollaborate with principal investigatorConduct literature searches.Conduct university research Design scientific experimentsGuide studentsInterpret scientific dataManuscript preparationOral presentationOrganise meetingsPrepare regulatory documentsPresent data at congressPublication of articlesSolve problemsSupervise techniciansUse laboratory techniquesWrite papers

Education

  • PhD in Medical Sciences from Ghent University in 2006
  • Bio-engineer in Cell and Gene Biotechnology from Ghent University in 2000

Languages

BrightOwl Assessment:
Self Assessment:
Dutch
Native
English
Full Proficiency
French
Elementary Proficiency

Work Preferences

  • Positions I am interested in:
    Associate Scientist Biomedical Scientist Clinical Research Consultant CMC Project Manager Lab Scientist Molecular Biologist Post-doctoral Fellow Preclinical Scientist R&D Scientist Regulatory Affairs Consultant Research fellow Scientific Writer Scientist Senior Scientist
  • Work From Home:
    No
  • Work Regime:
    Permanent position :    100 % FTE
    BrightOwl employee :    100 % FTE
  • International:
    No

Publications

    Expert has 7 publications (Will be avalible with full profile)

Area / Region

Belgium

Others

Driving License
  • Yes