Experience: PhD in Biomedical science.
Industry: Bio Pharma R&D (Biotherapeutics).
Development of monoclonal antibody (upstream and downstream development).
Maintainance and feed development in Bioreactor. Cell culture (mammalian cell lines).
First hand experience in life science research and techniques.
Expertise in cell culture, transfection, transformation, cell based assays ELISA and glucose uptake assay.
Expertise in Biochemical assays,Immunoprecipitation,Acetylation assay.
Experience in IHC, SDS PAGE, DNA/RNA purification, molecular biology techniques and RT PCR.
Project Management skills.
Worked in close collaboration with International research groups.
Project oriented approach for standardizing different techniques.
International education and outlook.
Worked independently as well as in groups, a multi functional team player.
Keen interest and experience in scientific research and scientific writing.
Junior Scientist Leuven, Belgium
August 2009 --- November 2013
A researcher / scientist with extensive experience in biomedical sciences and research garnered from both the academia and the pharmaceutical industry. Well rounded biologist with a background in molecular biology, cell biology and bio informatics. Proven ability to build upon and refine existing knowledge and technical expertise. Highly detail oriented with exceptional management and communication skills anchored by a strong publication record. Strongly passionate about applying scientific concepts and discoveries for disease mitigation and drug development. Proficient in assay development and troubleshooting complex systems. Well-versed in advanced scientific research techniques, analysis and scientific writing.
August 2009 --- November 2013
Neurodegenerative disorders like ALS (amyotrophic lateral sclerosis) disease account for a significant proportion of morbidity and mortality in both developed and developing world. As population ages, an improved understanding of these diseases will be vital to develop more effective therapies and combating the personal, social and economic well being . We studied synaptic defects / defects in neuronal communication in fruit fly models of ALS.
Junior Research Fellow Bangalore, Karnataka, India
August 2006 --- July 2009
Over 7 years of multi-disciplinary research experience with emphasis on developing scientific solutions for complex issues. Proven leadership and supervisory skills developed through mentoring graduate students, co-ordinating university wide events and leading journal publications.
Junior Research Fellow
August 2006 --- July 2009
Involved in design and execution of Cell line development part of a comprehensive research program aimed at the indigenous development of biologics/biosimilars. Responsible for planning and execution of transfection, selection, single cell cloning (limiting dilution), and finally conversion of serum dependent to serum independent clone. Have mastered the use of both adherent and suspension culture for clone development. Worked with different cell lines namely CHOk1, CHO-S, DG44 and HEK293. Have proficient knowledge in Cryopreservation, revival and cell banking. In addition, also performed in house media standardization for optimal growth and expression of the selected clone. Have performed bioactivity assay and also mycoplasma contaminant identification by Chemiluminenscence.
January 2006 --- June 2006
Diabetes Mellitus type 2 is a metabolic disorder with high blood sugar due to insulin resistance. I have studied Insulin mimicking and insulin sensitivity in different herbal extracts on mammalian cell lines.
CoordinationInterest in knowledgeKindnessOptimismProactivityProblem solvingSelf-confidenceSociabilityAdaptabilityAnalytical thinkingAttention to detailCollaborationCreative thinkingFlexibilityIndependenceResult Oriented
Biochemistry Cell biology Diabetes Lab scale batches R&D Scientific writingActions and modes of action of drugs in the human speciesAnimal ModelsAntibodiesBiomarkersBiopharmaceuticalsBiotechnologyCancerCell biologyCell CultureConfocal MicroscopyData ManagementDNADNA sequencingEnglishEnzyme-linked immunosorbent assay (ELISA)Fluorescence MicroscopyFluorescent microscopyGeneticsGood Laboratory Practice (GLP)GMPHPLCImmunofluorescenceImmunohistochemistry (IHC)ImmunologyImmunoprecipitationIn VitroIn VivoMicrobiologyMicroscopyMicrosoft ExcelMicrosoft OfficeMolecular & Cellular Biologymolecular biologyMolecular CloningNeurologyNeurosciencePCRpeople managementPharmaceutical IndustryPilot scale batchesPowerPointProject ManagementProtocolR&DQuantitative PCR (qPCR)RT-PCRScientific WritingSOPTeam LeadershipTechnical reportsTransfectionVaccinesWestern BlottingWriting Study Procedures and SOPs
Skills and Expertise
Analyze data Create SOPs Develop protocols Guide students Interpret data Lab scale batches Report data Use a confocal microscopy Write papersAdjust methodsAdjust processes Adjust processes and methodsAnalyze dataAnalyze proteinAssign activitiesAssist with experimentsAssist with proceduresAttend seminarsComplete study proceduresData analysisCreate study documentsData miningData entryData verificationDesign protocolDesign studyDesign study documentsEnsure good clinical practice (GCP)General office managementGuide staffLiaise with research teamlifescienceMaintain Quality Management System (QMS)Manage laboratory proceduresManuscript preparationManuscript preparation and reviewManuscript reviewOffice managementOral presentationOrganise meetingsPilot scale batchesPresent data at congressProvide trainingPublication of articlesPublish scientific projectsReferral lettersReview study protocolsWrite papersWrite protocolsWritten presentation
Ph.D. in Biomedical Sciences from Katholic Universitry of Leuven in 2013
Master of Science (MSc) in Biotechnology from Amrita Centre for Biotechnology in 2006
Bachelor in Biotechnology and Botany from St. Berchmans College,Mahatma Gandhi University,Kerala,India in 2004
Expert has 3 publications (Will be avalible with full profile)