Active in pharmaceutical drug product formulation development of poorly soluble small molecules.
Experienced in screening and formulation development of oral and IV nanosuspensions, microsuspensions, solutions, SEDDS and emulsions.
Some experience in microsuspensions and building up knowledge and experience about solid disperions + DSC analysis.
GMP experience: Total production of an IV nanosuspension (low shear milling) and some smaller projects.
Always interested and eager to learn new techniques or insights about anything which concerns the (liquid) pharmaceutical drug development.
Scientist Ghent, Belgium
Since September 2013
Formulation Research & Development, liquid dosage forms.
Lead Scientist for R&D Projects with the focus on:
- Screening and formulation of oral and IV nanosuspensions (high shear and low shear milling process)
- Screening and formulation of IV solutions
- Screening and formulation of Self-Emylsifying Drug Delivery Systems (SEDDS)
- Screening and formulation of Microsuspensions
- Formulation optimization of an eye emulsion
Some additional R&D experience in:
- Solid Disperions + DSC analysis
GMP Operator for Amatsi SEPS CTM (Clinical Trial Manufacturing)
- Total production of an IV nanosuspension
- Some additional smaller productions
Research Scientist Ghent, Belgium
February 2012 --- June 2012
Research about the pharmaceutical applications of the Surface Acoustic Wave biosensor.
Publication available in Dutch: http://lib.ugent.be/fulltxt/RUG01/001/894/582/RUG01-001894582_2012_0001_AC.pdf
CuriosityAdaptabilityCollaborationSociabilityProblem solvingOrganizationKindnessEfficiencyStrategic thinkingResult OrientedProactivityFlexibilityInnovative thinkingInterest in knowledgeOptimismIndependence
Phase I R&DBioavailabilityClinical DevelopmentDesigning case report formsEarly development stageGood Manufacturing Practice (GMP)Laboratory TechniquesLaboratory ResearchLaboratory study designPharmacokineticsPharmacodynamicsPhase IIRate of drug eliminationStrategic PlanningEnglishviscositysuspensionnanosuspensionmicrosuspensionintravenous self emulsifying drug delivery systems
Skills and Expertise
Lab scale batchesManufacture of GMP batchesManufacture of non-GMP batchesOperate research equipmentReport study conclusionsSetup of research equipmentSolve problems
Master in Farmaceutical Sciences from University Ghent in 2013
Training and Certification
APV basics: Preformulation training in 2015 Training
DSC theoretical and practical training course (TA Instruments) in 2015 Training