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Summary

Experienced research scientist (PharmD, PhD).
Currently studying at the KU Leuven to get his economics/management degree.

Experiences

Current Experience

  • Part-time student
    Since September 2013

Past Experience

  • Sabatical leave
    October 2012 --- September 2013

  • Senior Scientist Pharmacokinetics - Dept of Pharmacology
    November 2008 --- September 2012
    * Provide expert advice on pharmacokinetics (PK) and pharmacodynamics (PD) of therapeutic proteins (Nanobody® technology), including modelling and simulations support; * Planning, designing, monitoring, analyzing, reporting and presenting results of non-clinical PK/PD studies; * Interfacing/collaborating with other departments including bioanalytics, in vitro and in vivo pharmacology, toxicology, CMC, biostatistics, clinical operations, and regulatory affairs; * Liaise with external collaborators/researchers at academic institutions and CROs; * Efficient communication with project managers with respect to design, timing, resources and follow-up of ongoing studies, including timely and concise interpretation and communication of topline results; * Provide “competitive intelligence”, including follow up of applicable regulatory guidelines and industry best practices; * Provide input in Health Authority briefing packages, IB (Investigators Brochure), and IMPD (Investigational Medicinal Product Dossier), and responses to HA inquiries; * Represent Ablynx at scientific conferences (oral or poster presentations)

  • Principal Scientist / Lead Scientist DMPK
    June 2007 --- October 2008
    *Preparation of the preclinical DMPK strategy and implementation plan and integration in the global cross-functional development strategy *Preparation of registration and submission documents *Provide input to Health Authority briefing packages, IB, IMPD, CSD, CCDS, and Label (SPC/USPI), RMP, … *Point contact between the department of DMPK and the global Compound Development Team *Interfacing / collaboration with other departments including Clinical Pharmacokinetics, Advanced Modeling and Simulations (AMS), depts of Bioanalysis and Toxicology, and various Centers of Expertise (CoExp) *Provide “competitive intelligence” *Scientific input / review of DMPK, Clinical Pharmacology and Pharmacokinetics protocols, including third party research proposals / manuscripts *Evaluation of in-licensing opportunities / dossiers and *Study Director (SD)/Principal Investigator(PI)/Study Monitor (SM) of in vitro and in vivo metabolism, excretion, and drug-drug interaction studies

  • Senior Scientist / Lead Scientist DMPK
    July 2004 --- June 2007
    *Preparation of the preclinical DMPK strategy and implementation plan and integration in the global cross-functional development strategy *Preparation of registration and submission documents *Provide input to Health Authority briefing packages, IB, IMPD, CSD, CCDS, and Label (SPC/USPI), RMP, … *Point contact between the department of DMPK and the global Compound Development Team *Interfacing / collaboration with other departments including Clinical Pharmacokinetics, Advanced Modeling and Simulations (AMS), depts of Bioanalysis and Toxicology, and various Centers of Expertise (CoExp) *Provide “competitive intelligence” *Scientific input / review of DMPK, Clinical Pharmacology and Pharmacokinetics protocols, including third party research proposals / manuscripts *Evaluation of in-licensing opportunities / dossiers

  • Scientist DMPK
    June 2001 --- June 2004
    * Study Director (SD)/Principal Investigator(PI)/Study Monitor (SM) of a) absorption, distribution, and pharmacokinetic studies with radioactive (incl. QWBA) and non-radioactive drugs and b) toxicokinetic studies in various pre-clinical species As Study Director: Overall responsibility for the scientific conduct of a study and compliance of the study with the OECD Principles of Good Laboratory Practice As Study Monitor: coordination and scientific follow-up of outsourced studies (acting on behalf of the Sponsor) *Management of co-investigators involved in above mentioned studies *Pre-clinical Pharmacokinetics Representative: close collaboration with the Pre-clinical development leader and the Lead Scientist in the coordination of projects and the follow-up of departmental tasks.

Knowledge

LinkedIn Assessment :
PharmacokineticspharmacologyPharmacodynamicsDrug DevelopmentIn VitroIn VivoToxicologyAntibodiesPK/PDDrug metabolismModelingClinical pharmacologyBioanalysisBiologicalsBiologicsMedical writingProject ManagementEconomicsMarketingManagement AccountingStrategic Human Resources Leadership

Education

  • in Spanish - Level 4 from Center For Adult Education (The Perspective) in 2015
  • Master Of International Business Economics and Management in from KULeuven in 2015
  • PhD (summa cum laude) in Drug metabolism and Pharmacokinetics from Gent University in 2000
  • Ind. PharmD (magna cum laude) in Industrial Pharmacy from Free University of Brussels in 1997
  • Master's degree (cum laude) in Pharmaceutical Sciences from Free University of Brussels in 1995

Area / Region

Gent

Others

Driving License
  • Yes