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Summary

I am an immunologist with a strong foundation in medical and molecular biotechnology and a focus on inflammation and autoimmunity. My research is aimed to provide rationale and tools for the development of new therapeutic approaches in inflammation and immunological disorders, bridging the gap between academia and industry. Specialties: R&D, Research Management, Pre-Clinical Research, Research Design, Immunology, Medical Biotechnology

Experiences

Current Experience

  • Scientist - Bill and Melinda Gates Foundation Initiative
    Since July 2015
    As part of a collaboration between GlaxoSmithKline Vaccines (GSK) and the Bill & Melinda Gates Foundation (BMGF) leveraging systems biology to further advance the malaria and tuberculosis vaccine programs, my responsibilities include: - Coordinating a collaboration between GSK, The Bill and Melinda Gates Foundation, Stanford University, Emory University and Seattle Biomed to advance data analysis of vaccine trials. - Developing expertise with the CyTOF platform in analyzing samples obtained in a malaria human challenge clinical study. - Analyzing immunological and gene expression data collected in (pre)clinical studies aimed at improving our understanding of vaccine mode of action.

Past Experience

  • Marie Curie Postdoctoral Fellow
    July 2013 --- June 2015
    Working at GlaxoSmithKlilne Biologicals, my aim is to define the mechanisms of action of complex adjunvant systems to improve vaccination strategies.

  • Postdoctoral Research Fellow
    December 2011 --- May 2013
    My research here was aimed to understand the mechanisms underlying the development of Inflammatory Bowel Disease, a chronic intestinal pathology. Specifically, I investigated the role of IL-1b in intestinal immunity and the role of NOD2 in chronic models of intestinal inflammation.

  • DPhil Student, Sir William Dunn School of Pathology
    October 2007 --- October 2011
    The aim of my DPhil is to characterize the role of NOD-like receptors in the pathogenesis of inflammatory bowel disease. In particular, my research is focused on analyzing the role of the NLR-triggered cytokine interleukin-1 in innate and T-cell driven model of disease. Moreover, I aim to assess how the NLR NOD2 is involved in the development of inflammatory bowel disease.

  • Research Assistant
    September 2006 --- July 2007
    My work in Dr.Marika Falcone's lab was focused in setting up a new research line to analyze the role of regulatory immune cell compartment in the intestinal mucosa of patients with type 1 diabetes and celiac disease. I succesfully liaised with medical doctors in San Raffaele Hospital and helped organizing a team of surgeons, clinical investigators and researchers towards our common aim.The standard methods and preliminary results I obtained allowed this work to be financed by the Juvenile Diabetes Research Fund.

Knowledge

Self Assessment :
Innate immunity Animal modelsFlow CytometryImmunofluorescenceInfectious diseases R&D Scientific writingData AnalysisAutoimmune Diseases BiostatisticsProject Management
LinkedIn Assessment :
ImmunologyMucosal ImmunologyFACS analysisMicrosatellite genotypingmolecular biologyCell Based AssaysCell CultureMicroscopyConfocal MicroscopyHistologyExperimental DesignData AnalysisCellFlow CytometryInflammationIn VitroGeneticsIn VivoDrug Discovery

Education

  • DPhil in Immunology from University of Oxford in 2011
  • Master in Science in Medical Biotechnology from Libera Università Vita-Salute San Raffaele in 2006
  • Master in Science in Medical Biotechnology from Libera Università Vita-Salute San Raffaele in 2006
  • B.Sc. in Biotechnology from Sapienza Università di Roma in 2004

Area / Region

Belgium

Others

Driving License
  • Yes