I am a talented and determined scientist with a sound expertise in the fields of Molecular Biology, Oncology, Cell Biology and Pre-Clinical Drug Development. I am also passionate about all the innovations in the Biomedical area. Throughout my PhD and post-Doctorate experiences I built up a long standing expertise in team-oriented and international environment and I developed excellent writing, communication and presentation skills.
Regulatory Submission Coordinator
Since January 2016
• Distribute, track, review, and approve individual site trial master file (TMF) essential documentation at project start • Collect, review, organize, and assemble regulatory submissions • Maintain timelines for study start-up submissions and all subsequent submissions • Provide advice and guidance to internal and external team members to ensure compliance with applicable regulations and requirements • Review pertinent regulations and guides to develop proactive solutions to clinical trial submissions issues and challenges • Collaborate with document center to ensure necessary documentation is present • Train and assist CRAs on the collection of essential documentation for the ongoing phase of the project
Post doctoral fellow
January 2014 --- January 2015
TECHNIQUES: CRISPR/Cas9, design and optimization of qPCR primers, in vivo work (art. 9 certification), cell-based assays, molecular cloning, SDS PAGE, immunocytochemistry, Microsoft Excel, PowerPoint, Word, Outlook and GraphPad Prism PROJECTS & TASKS • Generation of transgenic in vitro and in vivo models to assess the contribution of hypoxic cells to tumor development and response to radiotherapy • Validation of new genes potentially involved into Notch1 pathway • Scientific publications, advising and training of PhD and undergraduate students.
January 2010 --- January 2014
TECHNIQUES cell/bacterial cultures, in vivo experiments, cell-based assays, transfections, molecular cloning, recombinant protein production, PCR, qPCR, SDS PAGE, ChIP, flow cytometry, immunoprecipitations, fluorescent microsopy,Microsoft Excel, PowerPoint, Word, Outlook and GraphPad Prism PROJECTS & TASKS • Characterization of DRAGO, a new potential oncologic therapeutic target using Molecular and Cell Biology techniques and in vivo models • Review of grant proposals, presentations at international conferences • Scientific publications, supervision and training of undergraduate students
January 2008 --- January 2010
TECHNIQUES cell/bacterial cultures, cell-based assays, transfection & clone selection, molecular cloning, recombinant protein production, PCR, qPCR, SDS PAGE, immunoprecipitations, fluorescent microsopy, Microsoft Excel, PowerPoint, Word, Outlook and GraphPad Prism PROJECTS & TASKS • Role of K-Ras mutations in in non-small-cell lung cancer's drug resistance. Employed cell lines and drug regimens mimicking oncologY patients’ condition. • COLLABORATION with Biophysics Department of St. Petersburg State Polytechnic University: influence of extracellular copper concentration on cisplatin uptake and tumor growth in mouse models. • COLLABORATION with the Cancer Chemoprevention Group of the University of Leicester: anticancer properties of a plant-derived flavonoid in mouse models. • Scientific publications, supervision and training of summer students.
Analytical thinkingAdaptabilityApproachabilityAttention to detailCollaborationIndependenceInterest in knowledgeOrganizationProactivityProblem solvingResponsibilityResult OrientedSelf-confidence
PhD in Life and Biomolecular Sciences in Oncology and Cancer Biology from The Open University in 2014
Post Graduate Specialization in Pharmacological Research in Oncology and Cancer Biology from Mario Negri Institute for Pharmacological Research in 2010
Master of Science (M.Sc.) in Biotechnology from Università degli Studi di Milano-Bicocca in 2008
Bachelor of Science (B.Sc.) in Biotechnology from Università degli Studi di Milano-Bicocca in 2005