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Summary

I am a creative and versatile scientist, passionate about the study and application of biomacromolecules. Specialties: Molecular biology, recombinant protein production, biophysical protein characterization, bioconjugation, homogeneous catalysis, organometallic chemistry

Experiences

Current Experience

  • Scientist
    Since July 2013
    Development of an LSPR technology platform to detect biomolecular interactions Development of new bioconjugation methods for coupling proteins onto functionalised nanomaterials

Past Experience

  • Research Scientist, Chemistry
    May 2013 --- June 2013
    -Responsible for the design, synthesis, purification and Q&A of siRNA conjugates.

  • Scientist
    November 2012 --- April 2013
    Development of an LSPR technology platform to detect biomolecular interactions Development of new bioconjugation methods for coupling proteins onto functionalised nanomaterials

  • Research fellow
    July 2009 --- June 2011
    Promoted by the University of St Andrews

  • Wetenschappelijk medewerker
    July 2005 --- June 2009
    Aim Merge molecular recognition properties of biomolecules (proteins, peptides and DNA) with transition-metal catalysts to create artificial metalloenzymes for highly selective homogeneous catalysis Research activities ■ Production and structural engineering of recombinant proteins ■ Bioconjugation of transition-metal catalysts ■ Analysis proteins and hybrid protein-catalyst systems ■ Analysis DNA and hybrid DNA-catalyst systems ■ Application hybrid systems in catalysis Major achievements ■ Developed first methodology for covalent cysteine-specific   bioconjugation of phosphine-ligands to structurally diverse proteins ■ Synthesised a variety of hybrid protein/phosphine and    protein/nitrogen ligand metalloproteins, affording artificial    metalloenzymes for transition-metal catalysed reactions Management ■ Managed all biochemical aspects of the research in the group ■ Trained undergraduate/PhD students and post-docs in molecular    biology and production/ purification/characterization of recombinant proteins ■ Co-supervised three PhD students (two have obtained their PhD)

  • PhD student
    June 2000 --- June 2005
    Biophysical characterization of photochemistry, structure and mechanisms of signal transduction in photoreceptor proteins

Knowledge

LinkedIn Assessment :
molecular biologyProtein PurificationProtein chemistryProtein AnalysisBioconjugationProtein EngineeringOrganic ChemistryCatalysisHPLCFPLCGC/MSLC-MSMass SpectrometryUV-Vis spectroscopyFluorescence SpectroscopyProposal WritingScientific WritingSupervisory ExperienceOrganometallic ChemistryBiotechnologyR&DNanomaterialsChemistryBioconjugationPeptidesrecombinant DNA technologyBiochemistry

Education

  • Drs/MSc in Chemistry/Molecular Microbiology from University of Amsterdam in 2000

Languages

BrightOwl Assessment:
Self Assessment:
Dutch
Native
English
Full Proficiency
French
Professional Proficiency

Work Preferences

  • Work From Home:
    No
  • Work Regime:
    Permanent position
  • International:
    No

Area / Region

Mortsel, Belgium

Others

Driving License
  • Yes