Since September 2014
- Development of assays for phage enumeration and efficacy testing; - Development of phage efficacy testing methods against a range of pathogens; - Support of sales department with validation and application experiments design for the phage-based products;
December 2012 --- April 2014
My work was focusing on interaction of EPEC (Enteropathogenic E. coli) with host intestinal epithelial cells and the mechanisms by which epithelial function is altered as a result of these infections. I was assessing the impact of effector proteins produced by EPEC on TJ structure, function and polarity complexes, by infecting cell lines using different effector combinations. Developing a new effectors delivery system based on lentiviral particles.
June 2012 --- September 2012
Bioengineering of lantibiotic lacticin3147 and LactococcinB bacteriocin.
FEBS Research Fellow/ Microbiology Laboratory Practical Demonstrator
February 2012 --- June 2012
Obtaining of new lactococcin B variants using a PCR-based mutation approach; Improving the technological attributes of nisin and lacticin 3147: improve pH, temperature, serum stability, protease resistance and/or production levels;
October 2008 --- March 2012
"Studies of bacteriocins produced by Lactococcus lactis strains" Isolation of lactic acid bacteria (LAB) from fermented food samples; Bioengineering of lacticin 3147; Bioengineering of lactococcin B. Comparison of the potency of the lipid II targeting antimicrobials nisin, lacticin 3147 and vancomycin against Gram positive bacteria.
Phd Student Trainee
January 2010 --- January 2011
Diploma Engineer in Food Biotechnology
October 2003 --- July 2008
Main subjects: Microbiology, Biochemistry, Food Biotechnology, Toxicology, Enzymology.
BSc in Food Biotechnology from Universitatea „Dunărea de Jos” din Galați in 2011