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Summary

phd in Neuroscience, i specialized in pre-Clinical pharmacology especially in neurodegenerative diseases. during my professional experiences, i acquired a strong expertise on new therapies to counteract the natural course of various diseases such as Alzheimer's disease, stroke as well as down syndrome.
to do so, i had to adapt the Treatment used (by recombinant Proteins, synthetic pharmacological products or by Gene transfer) based on the specifications imposed by the characteristics of each pathologies.
specialties: pharmacology, transfer of therapeutic genes, Pathophysiology, rodent behavior, Data Management, alzheimer, stroke, down syndrome.

Experiences

Current Experience

  • Postdoctoral Researcher

    CEA fontenay-Aux-Roses
    Since April 2011

    "development of rodent models of neurodegenerative disease by Gene transfer"​

    "pre-Clinical Development of treatments for cognitive deficits in Alzheimer's disease mouse models"​

    Publications:
    http://www.ncbi.nlm.nih.gov.gate2.inist.fr/pubmed/26141492
    http://hmg.oxfordjournals.org/content/early/2015/09/07/hmg.ddv268.abstract
    http://link.springer.com/article/10.1007/s00401-015-1498-9

    "Development of rodent models of neurodegenerative disease by gene transfer"​

    "Pre-Clinical Development of treatments for cognitive deficits in Alzheimer's disease mouse models"​

    Publications:
    http://www.ncbi.nlm.nih.gov.gate2.inist.fr/pubmed/26141492
    http://hmg.oxfordjournals.org/content/early/2015/09/07/hmg.ddv268.abstract
    http://link.springer.com/article/10.1007/s00401-015-1498-9

  • PhD student

    Hôpital Henri-Mondor Créteil, France
    Since October 2003

    "stroke Pathophysiology, modeling and neuroprotective studies."​

    Publications :
    http://www.ncbi.nlm.nih.gov/pubmed/16361106
    http://www.ncbi.nlm.nih.gov/pubmed/15545923
    http://www.ncbi.nlm.nih.gov/pubmed/14555245

    "Stroke pathophysiology, modeling and neuroprotective studies."​

    publications :
    http://www.ncbi.nlm.nih.gov/pubmed/16361106
    http://www.ncbi.nlm.nih.gov/pubmed/15545923
    http://www.ncbi.nlm.nih.gov/pubmed/14555245

Past Experience

  • Postdoctoral Researcher Paris, France

    October 2009 --- March 2011

    "Preclinical development of a gaba-a receptor α5 subtype inverse agonist in a mouse model of down syndrome: Analysis of genetic effects following chronic injection"​

    Publications :
    http://www.ncbi.nlm.nih.gov/pubmed/22028705
    http://www.ncbi.nlm.nih.gov/pubmed/24152333

  • Postdoctoral Researcher Orsay, France

    April 2008 --- September 2009

    "Preclinical development of a gaba-a receptor α5 subtype inverse agonist in a mouse model of down syndrome: Analysis of memory effects following acute injection"​

    publication :
    http://www.ncbi.nlm.nih.gov/pubmed/21693554

  • Researcher Parc Biocitech, 93210 Romainville

    February 2007 --- January 2008

    "establishment of left coronary artery occlusion rat model, efficacy study of cardioprotective compounds"

Knowledge

Self Assessment :
Animal models R&DActions and modes of action of human physiologyAnimal trialBiostatisticsBudget ManagementData ManagementIn VivoNeurosciencePre-clinical researchSurgery
LinkedIn Assessment :
Project ManagementalzheimerAnimal BehaviorStatisticsResponse to Calls for Proposals for funding projectsSupervision of PhD students and traineesSciences de la vieEstablishment of collaborationsmolecular biologyBiotechnologypharmacologyMemorybrainDown syndromephysiopathologyLife SciencesMicrosoft OfficestrokeResearchR&DBiotechnologieAlzheimer's diseasescienceBiologie molgestion de projetStatistiquesImmunohistochimie

Education

  • PhD in Neuroscience from Université Paris-Est Créteil (UPEC) in 2006
  • in from Université Paris-Est Créteil (UPEC) in 2003
  • in from Université Paris Sud (Paris XI) in 0000
  • in from in 0000

Languages

BrightOwl Assessment:
Self Assessment:
French
Native
English
Professional Proficiency

Area / Region

Fontenay-aux-Roses, France

Others

Driving License
  • No

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