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Summary

medicinal Chemist with a strong computer-aided Drug Design background and over 10 years of pharma & biotech experience.

Experiences

Past Experience

  • Platform Program Manager Diepenbeek

    August 2011 --- November 2015

    as platform Program Manager, i continued to provide cadd support for amakem's Drug Discovery and development projects. i also contributed as inventor to amakem's patent Applications, and provided scientific feedback in case of search reports and freedom to operate analyses. my tasks also included a fair amount of interaction with the Organic Synthesis and Biology groups at amakem, as well as contacts with external parties (cros, universities...).

  • Senior scientist - CADD

    August 2010 --- July 2011

    i joined amakem nv in 2010, a few months after it was incorporated. my inital tasks at amakem were:

    • to implement a small cadd platform based on open source contributions.
    • to provide cadd support in order:
      • to better define/understand the principles of the localized drug action platform
      • to optimize amakem's initial series of locally-acting rock inhibitors
      • to apply localized drug action principles to other compounds series and/or targets.

    successes in those tasks later resulted in a number of patent filings and in my promotion as platform Program Manager.

  • Research Scientist

    May 2008 --- December 2009
    * key competences: structure-based Drug Design, virtual screening, molecular docking, molecular dynamics, qsar/qspr, classification & regression Algorithms, cheminformatics * responsible for several lead Discovery & optimisation projects * redaction and presentation of proposals & scientific reports * contact with cros and compound providers * interaction with compound screening group

  • Senior Scientist

    May 2004 --- April 2008
    * key competences: structure-based and ligand-based Drug Design, virtual screening, molecular docking, molecular dynamics, qsar/qspr, homology modelling * support of the Medicinal Chemistry group for lead Discovery & optimisation projects * chem. rep. of a lead Discovery project involving virtual screening and crystallography * collaboration with fundp for Protein Purification and small Molecule crystallography projects * interaction with Organic chemistry, compound screening, and molecular biology groups

  • Doctorand (PhD Student)

    October 1999 --- February 2004

    * key competences: structure-based Drug Design, small Molecule crystallography, molecular docking, molecular modelling and molecular dynamics * support of a Drug Design project sponsored by regional funds (waleo) * phd studentship sponsored by two grants from the “fonds pour la recherche en industrie et en Agriculture” (fria) * collaboration with Organic chemistry and Molecular Virology groups * supervision of three first degree theses in the context of phd Research

Personality

Self Assessment :
AdaptabilityCollaborationCreative thinkingCritical thinkingCuriosityDependabilityIndependenceInterest in knowledgeProblem solvingAnalytical thinking

Knowledge

Self Assessment :
PharmacokineticsPharmacodynamicsBioavailability Scientific writing R&D BiochemistryScientific WritingPharmaceutical IndustryINDpharmacologyPowerPointMicrosoft ExcelMicrosoft OfficeActions and modes of action of drugs in the human speciesDrug metabolismChemistryMedicinal ChemistryMolecular ModelingPreclinical developmentLife SciencesDrug development processEDCEarly development stageIn VitroRegulatory affairsRisk Management
LinkedIn Assessment :
ExcelMedicinal ChemistryADMETDrug DesignMolecular ModelingAutodockPymolDockingCheminformaticsHomology ModelingMolecular DynamicsKnimeVirtual ScreeningEnzyme KineticsLife SciencesHit-to-leadChemistryProtein KinasesLifesciencesBioinformaticsScientific WritingDrug DiscoveryBiochemistryDrafting patent applicationsR&DResearchscienceLead OptimizationProtein chemistryComputational ChemistryMySQLLinuxQSARExcelADMETAutodockPymolHomology ModelingKnimeEnzyme KineticsHit-to-leadProtein KinasesLifesciencesScientific WritingDrafting patent applications

Skills and Expertise

Self Assessment :
lifesciencePublish scientific projects Write papers Report dataEvaluate physico-chemical dataResolves queriesOral presentationManuscript reviewManuscript preparationInterpret dataExecute scientific projects

Education

  • PhD in Sciences (Chemistry) from FUNDP (University of Namur) in 2004
  • Master in Chemistry from FUNDP (University of Namur) in 1999

Training and Certification

  • CRA Training in 2010 Training
  • HPLC Basics in 2010 Training
  • HPLC Methods Development in 2010 Training
  • Introduction to data management in 2010 Training
  • Introduction to good clinical practice in 2010 Training
  • Introduction to regulatory affairs in 2010 Training
  • Quality by Design in 2010 Training
  • Languages

    BrightOwl Assessment:
    Self Assessment:
    French
    Native
    English
    Professional Proficiency
    Dutch
    Elementary Proficiency
    Italian
    Elementary Proficiency

Work Preferences

  • Positions I am interested in:
    Project Manager Scientific Writer Scientific Researcher Scientific consultant Scientific Advisor Senior Scientist
  • Work From Home:
    No
  • International:
    No

Publications

    Expert has 20 publications (Will be avalible with full profile)

Area / Region

Eghezee, Belgium

Others

Driving License
  • Yes

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