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Summary

Pasteur Institute, DSM,

Experiences

Current Experience

  • Supervisor purification hepatitis B
    Since September 2015
    Supervision of the Purification part of the Bulk production process of hepatitis B Vaccine (Commercial batches) - Manages day to day vaccines operations related to purification steps and sterilizing filtration (grade A and B) . - Motivates and encourages teams of technicians and workers to achieve maximum productivity. Has authority for hiring, termination, discipline and performance decision. - Applies the recommended processes and anticipates potential improvements of the current processes while assuring compliance with the Change Management procedures. - Ensures compliance of the operations with GMP and Authorities requirements. Monitors quality of the production in close collaboration with QA and take corrective actions when necessary. Responsible to implement the Operational Excellence Process in the facility. - Represents his activities in external audits - Organises and monitors performance progress efficiency of the facility through Key Performance Indicators related to Quality, Budget, Delivery and Security. - Coordinate specific projects of improvement to ensure quality, efficiency, productivity, security. - Provide technical support to direct reports.

Past Experience

  • Graduate Trainee GIO - Value Stream HHM - Supervisor Purification Malaria
    March 2015 --- September 2015
    Supervision of the Purification part of the Bulk production process of Malaria Vaccine (Consistency and Commercial batches) - Manages day to day vaccines operations related to purification steps. - Motivates and encourages teams of technicians and workers to achieve maximum productivity. Has authority for hiring, termination, discipline and performance decision. - Applies the recommended processes and anticipates potential improvements of the current processes while assuring compliance with the Change Management procedures. - Ensures compliance of the operations with GMP and Authorities requirements. Monitors quality of the production in close collaboration with QA and take corrective actions when necessary. Responsible to implement the Operational Excellence Process in the facility. - Represents his activities in external audits - Organises and monitors performance progress efficiency of the facility through Key Performance Indicators related to Quality, Budget, Delivery and Security. - Coordinate specific projects of improvement to ensure quality, efficiency, productivity, security. - Provide technical support to direct reports.

  • Graduate Trainee GIO - Value Stream Bulk Synflorix
    September 2014 --- February 2015
    Mission part of the Talent Acquisition/Graduate Program Global Industrial Operations: 2-years training, 4 rotations of 6 months Shopfloor Position paper on the dissolved oxygen profile for protein D process Position paper on HVAC cascade pressure Improvement of the training module for DT/TT purification process PEMs improvement regarding the way of working and the use of the system Complete feasibility study (cost, time, efficiency, ressources) to replace a container in fermentation process

  • Graduate Trainee GIO - Supply chain and Logistics
    March 2014 --- September 2014
    Mission part of the Talent Acquisition/Graduate Program Global Industrial Operations: 2-years training, 4 rotations of 6 months Diagnose of the current weakness of the inventory strategy of the production site Determination of the replenishment costs for the company per type of articles Development of a personalized Inventory Strategy balancing the replenishment and carrying cost Creation of a manual to reapply and re-evaluate the model in the coming years

  • Graduate Trainee GIO - Validation
    September 2013 --- March 2014
    Mission part of the Talent Acquisition/Graduate Program Global Industrial Operations: 2-years training, 4 rotations of 6 months Validation of the serum irradiation used in several process within the vaccines industry Active part in the Design and Review of protocols and dose mapping Review of the results Definition and implementation of a quality and regulatory strategy regarding validation of irradiation process in general according to ISO 11137, EMEA, USP 1024, ICH Q5A and cGMP to assure optimal viral inactivation and performance of the product. Training of the department regarding irradiation process, validation and follow up Training and mentoring of a pharmacist intern regarding irradiation files

  • Coordinator New Product Development, New Product Introduction
    January 2013 --- September 2013
    Validation and qualification of all new raw materials used on GSK Vaccines production area (chemicals, biologicals, disposables, assemblies, complex medium, filters,...) Review of validation files according to industry standard (chemical compatibility, shelf-life,...) Definition of GSK requirements Creation of adequate monographs according to international standards (USP, PE) and GSK requirements External audit of the suppliers Management of manufacturer relationship from a quality point of view

  • Coordinator QA release Raw Materials
    July 2011 --- January 2013
    Quality and release of chemical compounds Management of process change for raw materials (RPC) Management of deviations and CAPA for raw materials Review and Closure of deviations and CAPA for Biologicals compounds Management of major vendors/manufacturers relationship from a quality point of view

  • Internship - Production-process engineer
    August 2010 --- February 2011
    Validated a pilot plant, Analyzed pH deviation and his influence on the product’s sensitivity Improved of the Delvotest® by performing experiments on Geobacillus spores’ parameter

  • Internship - Molecular Biology
    June 2009 --- August 2009
    Determination of amino acids residues responsible for the interaction between malT(transcriptional activator) and the RNA polymerase in E.coli key words: maltose, transcriptional activity, Kunkel mutagenesis,culture, plasmid,RNA polymerase, dosage beta-galactosidase

Knowledge

LinkedIn Assessment :
PurificationGMPChromatographyCell CultureFermentationProtein ExpressionImmunologyCellAffinityDNArecombinant DNA technologygenetic engineeringBiopharmaceuticalsQuality by DesignDownstream processingV&VIndustrial OrganizationPharmaceutical IndustryBiotechnologyBPF

Education

  • 2011 in Biotechnology - Production, Purification, Characterization of Biomolecules from ENSTBB - Institute of Biotechnology / Ecole Nationale Supérieure de Technologie des Biomolécules Bdx in 2011
  • 2006 Baccalauréat in Science (High school diploma) with a specialty in biology from 2006-2008 Polytechnicum of Bordeaux preparatory school in 2008

Area / Region

Brussels, Belgium

Others

Driving License
  • No