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Summary

- Extensive pre-clinical/early clinical research experience in cardiac pharmacology and regenerative medicine. - Pharmaceutical industry experience in drug discovery spans from target identification to early clinical development in both small molecules and biologic drug projects. - Proven track-record of accomplishments implementing and executing R&D strategies for drug discovery and development. - Senior role as scientific leader for drug development projects in different therapeutic areas. - Team leader experience coordinating lab-based scientist to support cross-functional drug project teams. - Author and co-author of multiple scientific publications in high impact factor journals and a strong network of academic collaborators worldwide.

Experiences

Current Experience

  • Associate Principal Scientist
    Since March 2014
    - Congestive heart failure (CHF) is a major cause of mortality worldwide with a steady increase in prevalence. There are multiple treatment options at hand to slow down disease progression, but currently no available cure beyond heart transplantation. - The fundamental pathology behind CHF is a loss in functional cardiomyocytes and diminished blood flow, which are not addressed by existing standard of care. - Our goal is to develop therapies for CHF patients by activating endogenous regenerative processes to replace the lost myocardium. If successful, such a therapy will offer a potential cure for patients who are dying of heart failure today and an entirely new treatment paradigm.

Past Experience

  • Senior Researcher | Assistant Professor
    January 2013 --- February 2014
    - The role of calcium signaling in cardiac cells is pivotal, as control the contraction and relaxation of the myocardium during every heart cells beat. - In addition, calcium signaling regulates mechanisms involved in the expression and repression of multiple genes. -Thus, not only the function, but also the fate of cardiac cells are geverned by calcium. - My research line focused on the integration of calcium signaling in controlling cell function and fate during cardiac development and regeneration.

  • Postdoctoral Researcher
    September 2009 --- December 2012
    As a postdoc scientist at Karolinska Intitutet, my research was focused on investigating the role of different calcium-dependent signaling mechanisms in controlling cell-fate determination in the context of stem cells differentiation, cardiomyocyte remodelling and cancer stem cells activation.

  • Research Assistant
    June 2007 --- September 2009
    - During my research period in Italy, I worked with genetically-manipulated animal models named "reporter mice". - This models allow the study of cellular processes through noninvasive, imaging-based methodologies, providing spatio-temporally insights of physiopathological events and long-term effects of xenobiotics. - My research was focused on analyzing the activation of liver estrogen receptor in response to nutrients availability, and the role of these signals in controlling the progression of the sexual cycle and fertility.

  • PhD student
    March 2003 --- May 2007
    Thesis title “Nuclear Calcium Signals induced by IGF-1 in Cardiac Myocytes: Characterization and functional mechanism” FONDAP Centro de Estudios Moleculares de la Célula, Facultad de Medicina, Universidad de Chile, Santiago, Chile. Main supervisor: Sergio Lavandero, PhD; co-supervisor: Enrique Jaimovich, PhD

  • Professor-Lecturer
    March 2004 --- December 2006
    Lecturer in Pharmacology and Toxicology

  • Professor-Lecturer
    March 2006 --- August 2006
    Lecturer in Biophysics and Cell Physiology

  • Pharmacist
    June 2002 --- December 2005

  • Student
    March 1996 --- September 2002
    Bachelor degree in Pharmaceutical Sciences Professional degree in Chemistry and Pharmacy

  • Pharmacist assistant
    May 1999 --- December 1999

Knowledge

LinkedIn Assessment :
Cell biologyBiochemistrymolecular biologyConfocal MicroscopyFluorescence MicroscopyMolecular ImagingEndocrinologyStem CellsCardiovascular MedicineCell SignalingCell Based AssaysAnimal ModelsAnimal handlingpharmacologyTeachingProposal WritingGrant WritingPhysiologyCellMedicineIn VitroIn VitroDrug DiscoveryLife SciencesPharmaceutical IndustryBiotechnologyCell CultureR&D

Education

  • Postdoctoral Researcher in Cell Physiology from Karolinska institutet in 2012
  • Doctor of Philosophy (Ph.D.) in Biomedical Sciences from Universidad de Chile in 2010
  • Bachelor of Pharmacy (B.Pharm.) in Chemistry & Pharmacy from Universidad de Chile in 2000

Languages

BrightOwl Assessment:
Self Assessment:
Spanish
Native
English
Full Proficiency
Italian
Full Proficiency

Work Preferences

  • Notice Period:
    12 weeks
  • Positions I am interested in:
    Principal Scientist
  • Work From Home:
    No
  • Work Regime:
    Permanent position :    100% FTE
  • International:
    Yes

Area / Region

Mölndal, Sweden

Others

Driving License
  • No