BrightOwl Loader Loading

Summary

my main Research field is In Vitro Drug metabolism. my Career goals is to apply and expand my knowledge in this field by supporting the development of safe and effective new drugs. my specific areas of expertise are (i) metabolite id and determination of Drug metabolism pathways, (ii) Enzyme Kinetics, (iii) reaction phenotyping, (iv) drug-to-drug interactions (direct and metabolism-based) and (v) method development and Validation (FDA guidelines). i have experience in using targeted (LC-MS/ms) and untargetted (lc-qtof) approaches, as appropriate. so far i worked with sub-cellular preparations, but i am eager to quickly learn how to work with hepatocytes. humans are the main species of interest, but i have knowledge to work with Animal models as rats and mice, too. my expertise suits well a "Drug metabolism and Pharmacokinetics" department of a pharma/biotech company, where i am seeking new Career opportunities.

Experiences

Past Experience

  • Post-doctoral Fellow

    July 2013 --- July 2015
    developed of Assays and Analytical methods to screen and characterize the In Vitro Metabolism of emerging flame retardants using untargeted (lc-qtof) and targeted (lc/ms/ms) approach.

  • Summer job

    June 2012 --- August 2012
    developed spectrophotometric In Vitro Assays to characterize the mechanism of action of drugs that metabolism-dependently inhibit cyp catalytic activity. Supervisor: dr. ryan takahashi department: Drug metabolism and Pharmacokinetics

  • Co-op Research Technichian

    April 2008 --- August 2008
    Research assistantship in Gel Electrophoresis for quantification of aromatase levels and development of a novel assay for bde-99 In Vitro Metabolism Supervisor: dr. stelvio bandiera faculty of Pharmaceutical Sciences

  • Research Assistant

    May 2005 --- May 2007
    investigated the toxicity of endocrine disrupting compounds in fish and the bioaccumulation of pollutants in fish and macroinvertebrates. Supervisor: dr. luigi viganò

  • Research thesis

    March 2003 --- May 2004
    title: In Vivo estrogenicity of benzylidene camphor and n-butylparaben in brown trout (salmo trutta) and zebrafish (danio rerio) Supervisor: prof. poul bjerregaard publication: bjerregaard, p., hansen, p.r., larsen, j.k., erratico, c., korsgaard, b., holbech, h., 2008. vitellogenin as a Biomarker for estrogenic effects in brown trout, salmo trutta: Laboratory and field investigations. environ. toxicol. chem. 27(11): 2387-2396.

Personality

Self Assessment :
CollaborationAdaptabilityAttention to detailCommunicativeCritical thinkingCuriosityFlexibilityIndependenceOptimismOrganizationProactivityResponsibilityResult Oriented

Knowledge

Self Assessment :
Drug metabolismKnowledge of the drug development processPreclinical ResearchLaboratory ResearchEnzyme KineticsReaction phenotypingin vitro in vivo clearanceCYPUGTsmetabolite IDInhibition of enzyme activityAnalytical ChemistryLC-MS/MS LC-QTOF Scientific writingHPLC
LinkedIn Assessment :
ResearchTeachingAnalytical ChemistryIn vitro metabolismEnzyme KineticsReaction phenotypingInhibition of enzyme activityElucidation of metabolite structuresIn vitro/in vivo clearance extrapolationLC-MS/MSLC-QTOFMass SpectrometryEnvironmental ScienceScientific WritingSpectroscopyChromatographyscienceLC-MSLaboratoryLife SciencesIn VitroChemistryHPLC

Skills and Expertise

Self Assessment :
Create SOPs Develop protocols Guide students Interpret data Write papers Write protocolsAdvise on strategyAssist with experimentsCoachcollaborate in research projects at universitiesCollaborate with project teamDesign scientific experimentsInterpret scientific dataPlan experimentsPrepare manuscriptProvide trainingPublication of articles

Education

  • On-line course in Drug development from University of California - San Diego in 2016
  • Doctor of Philosophy (Ph.D.) in Pharmaceutical Sciences (in vitro drug metabolism) from The University of British Columbia in 2013
  • Master's degree in Environmental Sciences from Università degli Studi di Milano-Bicocca in 2004

Languages

BrightOwl Assessment:
Self Assessment:
Italian
Native
English
Full Proficiency
French
Elementary Proficiency

Work Preferences

  • Notice Period:
    1 week
  • Positions I am interested in:
    Junior Scientist
  • Locations I am interested in:
    Austria Canada France Switzerland
  • Work From Home:
    No
  • Work Regime:
    Permanent position
  • International:
    Yes

Publications

    Expert has 23 publications (Will be avalible with full profile)

Area / Region

Antwerp, Belgium

Others

Driving License
  • Yes

Similar Candidates

Other Candidates in Belgium

Other Candidates in Antwerp

Other similar Candidates in Antwerp

Other Candidates

Most Recent Searches

Most Famous Searches

You might also like