BrightOwl Loader Loading

Summary

A self-motivated and results-oriented scientist with 20 years of experience in Life Sciences, including biotechnology, oncology and dermatology research.   

Experiences

Current Experience

  • Doctor-assistant (PhD) Ghent, Belgium
    Since October 2011

    • Optimization of in vitro and ex vivo psoriasis models
    • Testing (topically or systemic) of novel therapeutics (siRNAs, small molecules) against psoriasis in ex vivo 3D reconstructed skin models
    • Involved in the identification of potential biomarkers to predict therapeutic response to biologicals in psoriasis patients
    • Involved in the establishment of a Biobank for immunologic skin disorders (in collaboration with Bimetra, UZ Ghent and implementation of SLIMS software)
    • Supervisor of lab technicians and PhD students (co-promotor)
    • Practical guidance of PhD students appointed on an IWT-TGO project in collaboration with Galapagos N.V., Mechelen and Galapagos, SASU (Romainville, France) (Oct 2013-Dec 2016), and research meetings (2x/year)
    • Lab and project management
    • Project writing and medical, technical writing (SOPs, Ethics Committee applications)
    • Peer review assessment of research work and research project proposals of other groups
    • Budget calculations (pre-awards) and financial control of grants
    • Scientific reporting and publishing of data in peer-reviewed scientific journals
    • Teaching
    • This work resulted in 26 peer-reviewed papers of which 3 as first and 3 as last author (More info at https://biblio.ugent.be/person/801001025732)

Past Experience

  • POSTDOCTORAL SCIENTIST, FWO Ghent, Belgium
    October 2005 --- September 2011

    • Introduction and application of RNA interference (transient or stable) to silence specific isoforms of the motor protein myosin Va in order to inhibit melanosome transport in human primary melanocytes. This work resulted in patent application PCT Pub. No. WO2007/068704 A1, published on the 21st of June, 2007
    • Start-up of miRNA profiling of melanocytes followed by validation (qPCR, western blots, immunohistochemistry) and functional assays (transfections, luciferase assays) to identify target genes of aberrant miRNAs
    • Involved in the development of ultradeformable liposomes to deliver siRNA to the skin topically
    • Establishment of a 3D ex vivo reconstructed skin model (for use in depigmentation studies, topical application of molecules…)
    • Involved in the identification of genes or pathways playing a role in immune resistance in melanoma (FFPE material or blood samples)
    • Supervisor of PhD students and lab coordination (incl. biosafety)
    • Attending workshops and international meetings (+ presentation of own research work)
    • This work has led to 17 peer-reviewed papers of which 4 as first and one as last author

Personality

Self Assessment :
AdaptabilityAssertivenessCollaborationCommunicativeCompetitivenessCritical thinkingFlexibilityInterest in knowledgeKindnessProblem solvingResult OrientedSelf-disciplineSociabilityTrust

Knowledge

Self Assessment :
BiotechnologyBiomarkersBudget ManagementCell CultureCoachingDrug DeliveryProject ManagementRT-PCRScientific WritingInflammation

Education

  • PhD in Medical Sciences from Ghent University in 2002
  • Master in Biotechnology from Ghent University in 1995
  • Bachelor in Chemistry from Ghent University in 1993

Languages

BrightOwl Assessment:
Self Assessment:
Dutch
Native
English
Full Proficiency
French
Professional Proficiency

Work Preferences

  • Locations I am interested in:
    Aalst, Belgium Bruges, Belgium Ghent, Belgium Kortrijk, Belgium
  • Work From Home:
    Yes, 0 to 1 days per week
  • Work Regime:
    Permanent position :    100% FTE
  • International:
    No

Area / Region

Lovendegem, Belgium

Others

Driving License
  • Yes